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Thread: Different types of COVID-19 vaccines: How they work

  1. #1

    Post Different types of COVID-19 vaccines: How they work

    This is just layman comment. Of the three main types, description of subunit vax like Novavax below does not include terms genetic or RNA, that appears to make it the "most natural" of the three types (if the term natural could be at all used here).
    Have not validated this info:



    Different types of COVID-19 vaccines: How they work

    Curious about how mRNA vaccines and other types of COVID-19 vaccines can help you develop immunity to the COVID-19 virus? Understand how different technologies work with the immune system to provide protection.

    By Mayo Clinic Staff

    A coronavirus disease 2019 (COVID-19) vaccine can prevent you from getting COVID-19 or from becoming seriously ill or dying due to COVID-19. But how do the different types of COVID-19 vaccines work?

    Each COVID-19 vaccine causes the immune system to create antibodies to fight COVID-19. COVID-19 vaccines make use of a spikelike structure on the surface of the COVID-19 virus called an S protein. The S protein helps the COVID-19 virus get inside your cells and start an infection.

    The main types of COVID-19 vaccines currently available in the U.S. or being studied include:


    • Messenger RNA (mRNA) vaccine. This type of vaccine uses genetically engineered mRNA to give your cells instructions for how to make the S protein found on the surface of the COVID-19 virus. After vaccination, your immune cells begin making the S protein pieces and displaying them on cell surfaces. This causes your body to create antibodies. If you later become infected with the COVID-19 virus, these antibodies will fight the virus.
      After delivering instructions, the mRNA is immediately broken down. It never enters the nucleus of your cells, where your DNA is kept. Both the Pfizer-BioNTech and the Moderna COVID-19 vaccines use mRNA.
    • Vector vaccine. In this type of vaccine, genetic material from the COVID-19 virus is placed in a modified version of a different virus (viral vector). When the viral vector gets into your cells, it delivers genetic material from the COVID-19 virus that gives your cells instructions to make copies of the S protein. Once your cells display the S proteins on their surfaces, your immune system responds by creating antibodies and defensive white blood cells. If you later become infected with the COVID-19 virus, the antibodies will fight the virus.
      Viral vector vaccines can't cause you to become infected with the COVID-19 virus or the viral vector virus. Also, the genetic material that's delivered doesn't become part of your DNA. The Janssen/Johnson & Johnson COVID-19 vaccine is a vector vaccine. AstraZeneca and the University of Oxford also have a vector COVID-19 vaccine.
    • Protein subunit vaccine. Subunit vaccines include only the parts of a virus that best stimulate your immune system. This type of COVID-19 vaccine contains harmless S proteins. Once your immune system recognizes the S proteins, it creates antibodies and defensive white blood cells. If you later become infected with the COVID-19 virus, the antibodies will fight the virus.
      Novavax is working on a protein subunit COVID-19 vaccine.

    The U.S. Food and Drug Administration has given emergency use authorization to the Pfizer-BioNtech, Moderna and Janssen/Johnson & Johnson COVID-19 vaccines. The FDA and the Centers for Disease Control and Prevention have recommended that use of the Janssen/Johnson & Johnson vaccine continue in the U.S. because the benefits outweigh the risks. If you are given this vaccine, you should be educated about the possible risks and symptoms of a blood clotting problem. More types of vaccines are expected to be authorized for use in the coming months.

    mayoclinic.org/diseases-conditions/coronavirus/in-depth/different-types-of-covid-19-vaccines/art-20506465



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  3. #2
    None of these are Vaccines.

    They are experimental Gene Therapy.
    Liberty is lost through complacency and a subservient mindset. When we accept or even welcome automobile checkpoints, random searches, mandatory identification cards, and paramilitary police in our streets, we have lost a vital part of our American heritage. America was born of protest, revolution, and mistrust of government. Subservient societies neither maintain nor deserve freedom for long.
    Ron Paul 2004

    Registered Ron Paul supporter # 2202
    It's all about Freedom

  4. #3
    I got all three, just to be safe.
    Pfizer Macht Frei!

    Openly Straight Man, Danke, Awarded Top Rated Influencer. Community Standards Enforcer.


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  5. #4
    Quote Originally Posted by pcosmar View Post
    None of these are Vaccines.

    They are experimental Gene Therapy.
    Based on your understanding, both a and b would also impact genes?

    a) an unvaccinated person getting infected from the so called "covid-19" virus
    b) a person getting protein subunit vax like Novavax (non-mRNA and supposed to contain parts of the covid-19 virus)

    • Protein subunit vaccine. Subunit vaccines include only the parts of a virus that best stimulate your immune system. This type of COVID-19 vaccine contains harmless S proteins. Once your immune system recognizes the S proteins, it creates antibodies and defensive white blood cells. If you later become infected with the COVID-19 virus, the antibodies will fight the virus.
      Novavax is working on a protein subunit COVID-19 vaccine.


    Quote Originally Posted by Danke View Post
    I got all three, just to be safe.
    You might be inspiring Canada

    Canada to Allow Vaccine Mixing for Second Doses
    nytimes
    Jun 2, 2021 — Canada will soon allow vaccine mixing for second doses.






    In other press releases, this might be the first vax reporting 100% protection in any category:


    June 14, 2021 3:16 PM EDT

    Delta variant doubles risk of hospitalization; Novavax vaccine highly effective in large trial

    Nancy Lapid
    6 minute read

    June 14 (Reuters) - The following is a roundup of some of the latest scientific studies on the novel coronavirus and efforts to find treatments and vaccines for COVID-19, the illness caused by the virus.
    Delta variant doubles risk of COVID-19 hospitalization
    The delta variant of the coronavirus first identified in India may double the risk of hospitalization among COVID-19 patients, compared with the alpha variant first discovered in the UK, a study from Scotland suggests. Researchers looked at 19,543 COVID-19 cases and 377 hospitalizations among 5.4 million people, including 7,723 cases and 134 hospitalizations in patients with the delta variant, who tended to be younger and more affluent. The risk of COVID-19 hospital admission was about double with the delta variant compared to the alpha variant, with the risk particularly increased in those with five or more medical conditions known to contribute to more severe disease, the researchers reported on Monday in The Lancet. They found that two doses of the vaccines from Pfizer (PFE.N) and BioNTech and from AstraZeneca (AZN.L) still provide strong protection, although not as strong as the protection provided against the alpha variant. Two weeks after the second dose, the Pfizer/BioNTech vaccine was found to provide 79% protection against infection from the delta variant, compared to 92% against the alpha variant. With AstraZeneca's vaccine, there was 60% protection against delta compared with 73% for alpha. Because this was an observational study, more research is needed to confirm the findings, the research team said. (https://bit.ly/3xinW5K)
    Novavax vaccine highly effective in North American trial

    Novavax Inc (NVAX.O) on Monday said its COVID-19 vaccine was more than 90% effective, including against a variety of concerning coronavirus variants, in a large, late-stage clinical trial, providing another potential weapon against the disease once approved for use. In the trial involving nearly 30,000 volunteers in the United States and Mexico, the two-shot vaccine was 100% effective in preventing infection by the original version of the coronavirus, the company said. It was more than 93% effective against the predominant variants of the virus that have been of concern among scientists and public health officials.

    The alpha variant first identified in the UK was the predominant variant in the United States while the trial was being conducted, the company said. The vaccine was 91% effective among volunteers at high risk of severe infection and 100% effective in preventing moderate and severe cases of COVID-19. Novavax said the vaccine was generally well tolerated, with side effects similar to those seen with existing COVID-19 vaccines. The Novavax COVID-19 shot is a more conventional type of vaccine than those currently available. It contains an actual version of the virus' spike protein that cannot cause disease but can trigger the immune system directly. The company said the results put it on track to file for emergency authorization in the United States and elsewhere in the third quarter of 2021. (https://reut.rs/3iEvUlw)

    https://www.reuters.com/business/hea...ve-2021-06-14/

  6. #5
    Quote Originally Posted by enhanced_deficit View Post
    Based on your understanding,
    NO.
    Based on the Damn Definition.

    NOT a Vaccine.

    It is experimental Gene Therapy Falsely Called a Vaccine..

    Quit playing stupid Games.
    Liberty is lost through complacency and a subservient mindset. When we accept or even welcome automobile checkpoints, random searches, mandatory identification cards, and paramilitary police in our streets, we have lost a vital part of our American heritage. America was born of protest, revolution, and mistrust of government. Subservient societies neither maintain nor deserve freedom for long.
    Ron Paul 2004

    Registered Ron Paul supporter # 2202
    It's all about Freedom

  7. #6
    Quote Originally Posted by Danke View Post
    I got all three, just to be safe.
    I took three shots, and ate the worm for extra protection.
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  8. #7
    Quote Originally Posted by Brian4Liberty View Post
    I took three shots, and ate the worm for extra protection.
    I played in the dirt as a kid..

    and I have kissed dogs.
    Liberty is lost through complacency and a subservient mindset. When we accept or even welcome automobile checkpoints, random searches, mandatory identification cards, and paramilitary police in our streets, we have lost a vital part of our American heritage. America was born of protest, revolution, and mistrust of government. Subservient societies neither maintain nor deserve freedom for long.
    Ron Paul 2004

    Registered Ron Paul supporter # 2202
    It's all about Freedom

  9. #8
    Quote Originally Posted by pcosmar View Post
    and I have kissed dogs.
    TMI. Who you picked up at a bar at 2am doesn't belong in this discussion
    ...



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  11. #9
    Quote Originally Posted by RJB View Post
    TMI. Who you picked up at a bar at 2am doesn't belong in this discussion
    I have a Robust Immune System..

    But that does lead into my response to any asking My health status.
    Liberty is lost through complacency and a subservient mindset. When we accept or even welcome automobile checkpoints, random searches, mandatory identification cards, and paramilitary police in our streets, we have lost a vital part of our American heritage. America was born of protest, revolution, and mistrust of government. Subservient societies neither maintain nor deserve freedom for long.
    Ron Paul 2004

    Registered Ron Paul supporter # 2202
    It's all about Freedom

  12. #10
    Quote Originally Posted by pcosmar View Post
    ..
    and I have kissed dogs.
    Quote Originally Posted by RJB View Post
    TMI. Who you picked up at a bar at 2am doesn't belong in this discussion
    RJB, this is a family forum.. please.


    On an entirely unrelated topic and to give credit where due, brilliant minds behind current crop of vaccines were same ones who gifted mankind with other miracle vaccines in the past:

    'AIDS Vaccine'

    https://www.youtube.com/watch?v=NIWnl5zLBIM

  13. #11
    Quote Originally Posted by enhanced_deficit View Post


    On an entirely unrelated topic ]
    Only because you insist on Relating that unrelated Topic to every topic on the Forum..

    WTF is wrong with YOU?
    Liberty is lost through complacency and a subservient mindset. When we accept or even welcome automobile checkpoints, random searches, mandatory identification cards, and paramilitary police in our streets, we have lost a vital part of our American heritage. America was born of protest, revolution, and mistrust of government. Subservient societies neither maintain nor deserve freedom for long.
    Ron Paul 2004

    Registered Ron Paul supporter # 2202
    It's all about Freedom



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