Paxlovid has been deemed one of the gold standard Covid treatments in the U.S., even being touted by President Joe Biden at his State of the Union address this year.
Some of those who used the drug to treat the virus are reporting an interesting phenomena, though.
The drug, developed by Pfizer, is believed to be highly effective at preventing hospitalization or death in a person that has already been infected with the virus, but some who had their symptoms initially clear up after using the drug are reporting feeling symptoms again later on.
There are multiple reports that a people will also start testing positive for Covid once again after the five day treatment period concludes.
'We had three cases in the house with the same pattern,' John Donoghue, 71, told the Boston Globe.
'The symptoms the second time were milder ... in some ways, we feel that Paxlovid did its job. It took away the extreme symptoms of the first round and reduced them very quickly in all three cases.'
He reported that he, his wife and is mother, 95, all began to take the drug after contracted Covid.
Each started to feel better after using Paxlovid, but and even began to test negative, before their symptoms and positive test status returned once again.
Dr Paul Sax, an infectious disease expert at Brigham and Women's Hospital in Boston, told the Globe he had heard about the same occurring in patients as well.
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Experts told the Globe that the likely mechanism at play for the Donoghues, and others who have experienced similar phenomena can be described as a game of cat and mouse.
'It's literally that the Paxlovid is the cat, it suppresses the virus, and then when the cat's gone, the mice come out to play,' Dr. Michael Charness, chief of staff at Veterans Affairs Boston told the Globe.
'Paxlovid works really well while it's there, and for many people, they can eliminate the virus in a single phase of infection,'
'But for some people, maybe because it takes a little longer to ramp up immunity, they can't get rid of [all the virus] and the Paxlovid is no longer there to help.'
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More:
https://www.dailymail.co.uk/health/a...rus-again.html
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