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Thread: A vitamin that stops the aging process of organs

  1. #1

    A vitamin that stops the aging process of organs

    Nicotinamide riboside (NR) is pretty amazing. It has already been shown in several studies to be effective in boosting metabolism. And now a team of researchers at EPFL's Laboratory of Integrated Systems Physiology (LISP), headed by Johan Auwerx, has unveiled even more of its secrets. An article written by Hongbo Zhang, a PhD student on the team, was published today in Science and describes the positive effects of NR on the functioning of stem cells. These effects can only be described as restorative.

    As mice, like all mammals, age, the regenerative capacity of certain organs (such as the liver and kidneys) and muscles (including the heart) diminishes. Their ability to repair them following an injury is also affected. This leads to many of the disorders typical of aging.

    Mitochondria: also useful in stem cells

    Hongbo Zhang wanted to understand how the regeneration process deteriorated with age. To do so, he teamed up with colleagues from ETH Zurich, the University of Zurich and universities in Canada and Brazil. Through the use of several markers, he was able to identify the molecular chain that regulates how mitochondria - the "powerhouse" of the cell - function and how they change with age. The role that mitochondria play in metabolism has already been amply demonstrated, "but we were able to show for the first time that their ability to function properly was important for stem cells," said Auwerx.

    Under normal conditions, these stem cells, reacting to signals sent by the body, regenerate damaged organs by producing new specific cells. At least in young bodies. "We demonstrated that fatigue in stem cells was one of the main causes of poor regeneration or even degeneration in certain tissues or organs," said Hongbo Zhang.

    This is why the researchers wanted to "revitalize" stem cells in the muscles of elderly mice. And they did so by precisely targeting the molecules that help the mitochondria to function properly. "We gave nicotinamide riboside to 2-year-old mice, which is an advanced age for them," said the researcher. "This substance, which is close to vitamin B3, is a precursor of NAD+, a molecule that plays a key role in mitochondrial activity. And our results are extremely promising: muscular regeneration is much better in mice that received NR, and they lived longer than the mice that didn't get it."

    A breakthrough for regenerative medicine

    Parallel studies have revealed a comparable effect on stem cells of the brain and skin. "This work could have very important implications in the field of regenerative medicine," said Auwerx. "We are not talking about introducing foreign substances into the body but rather restoring the body's ability to repair itself with a product that can be taken with food." This work on the aging process also has potential for treating diseases that can affect - and be fatal - in young people, like muscular dystrophy (myopathy).

    More at: https://medicalxpress.com/news/2016-...min-aging.html
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  3. #2
    For every 100,000 stories like this, one turns out to be true. Could be less than that.
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  4. #3
    Quote Originally Posted by Brian4Liberty View Post
    For every 100,000 stories like this, one turns out to be true. Could be less than that.
    How many of those were true but suppressed and withheld for the ruling class?
    RBG should be dead many times over.
    Never attempt to teach a pig to sing; it wastes your time and annoys the pig.

    Robert Heinlein

    Give a man an inch and right away he thinks he's a ruler

    Groucho Marx

    I love mankind…it’s people I can’t stand.

    Linus, from the Peanuts comic

    You cannot have liberty without morality and morality without faith

    Alexis de Torqueville

    Those who fail to learn from the past are condemned to repeat it.
    Those who learn from the past are condemned to watch everybody else repeat it

    A Zero Hedge comment

  5. #4
    I agree with you. It depends on who and how you believe. Have you heard of CBD oils tinctures? Do you think it has the same effect?

  6. #5
    I tried this and found that it made me feel kinda bad. So what I did was take half of it to see if I could tolerate it.I can't really tell if it doing anything. I do take C60 and Co-Enzyme Q10(200mg) everyday and these 2 things to be something that I actually can feel. Usually if I feel sluggish it is because I haven't taken it.

    I am not necessarily interested in extending my life but, I do want what life I have left to be as healthy as possible. C60 helps the body make stem cells and COQ10 supports the mitochondria of the cells. I do eat a very healthy diet and I think that is the real backbone of good health.

  7. #6
    I've been taking nicotinamide off and on since 2014. I take it for non melonoma skin cancer. Over a year ago I upped my dosage. One 500mg pill when I wake up and one 500mg pill at supper time. I have no reaction to the vitamins I feel the same as when I don't take them.

  8. #7
    I only have about five minutes (if that) of direct sun exposure per day, usually walking to and from my car, and then on some days 30-60 minutes of sun exposure through the window of my car while driving. Other than that, I've been using vitamin C serum and supplements https://immunedefence.info/home to boost my immunity.
    Last edited by harryjosh; 01-06-2021 at 11:51 AM.



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