Old malaria drug might prevent and treat COVID-19

[osan]

TONS (literally) of Vitamin C for IV drips were shipped to China, it was so much in demand, so there are suppliers out there already ramping up production.

Facebook banned us after we published this, tagging it as "fake" news, so this information is being suppressed.

Story: https://healthimpactnews.com/2020/to...n-wuhan-china/

Heh... FB are a raft of überphagz. I just got canned for posting "Wuhan virus. Sue me." They are like bald-faced tyrants who make no pretense to anything better. Imagine if those people were in governmental power; the concentration camps would be many and full to bursting with VERY skinny people.

[nobody's_hero]

jmdrake: I am going to potentially concede this point to you, after I research it more. I have a healthy distrust of pharmaceutical products and maybe jumped the gun here, but if these drugs have been proven safe and effective against viral infections, I agree it should be part of the solution, and will even help promote it as such.

I will post later on my research.

Nothing wrong with a healthy distrust of pharmaceutical companies. If this were a new medication and not one that has been out since WWII with well-documented side effects I would be hesitant for sure to ever want it used on myself. Again, it's about risk versus benefits and for someone about to die, if this drug is showing promise then go for it.

[osan]

so i should just stick with bourbon

This is RIGHT thinking.

Carry on.

[ATruepatriot]

I'm not at liberty to give too much information because of HIPPA restrictions, but we have some high-probability COVID-19 patients at the small rural hospital where I work. The unfortunate thing about it is that the few testing kits we have must be sent out and may take days to get results. By the time their test results come back, I might already be showing symptoms, because I have been involved in their care.

In their current condition, I can assure you that these patients are not concerned with potential side effects of Plaquenil (hydroxychloroquine). One patient was placed on a ventilator early this week and another was intubated as I left work this morning. They are both older than 70. Both at high-risk. One may not live.

Modern medicine is a lot about risks versus benefits. If these were young patients with mild symptoms who weren't coughing so severely they can't take a breath and running high fevers (I'm talking >104F, which is very significant for seniors because the elderly usually do not run high fever), I'd say it might be worth worrying about things like long term kidney damage or heart failure.

IV vitamin bags will not do these patients any good at this point. While I am all about natural remedies over pushing pills on people, there comes a point where you have to honestly say what will be most effective in the moment. There are a lot of doctors out there who are more about running tests for big pharma than actually practicing the skills that doctors have utilized long before Pfizer or Glaxo-Smith-Kline started packaging pills.

The scary thing for me is that as a healthcare worker in the ER who is required to come in contact with these patients . . . our gowns, gloves, and simple mask/respirator supplies are running low. What's worse, is that when the PPE gets wet, it loses effectiveness. Anyone who has ever worn these things knows that the materials do NOT breathe, and you WILL sweat. A LOT. I'm more than a little nervous right now that I might be personally in for a rough few weeks, but like I said, I won't know until symptoms show. If I stop posting in the next few days, y'all can assume what happened.

One good thing about this whole thing, is that we are seeing a lot less 'nonsense' cases in the emergency department. People are heeding warnings and not going to hospitals unless having a true emergency that cannot wait. That's really the way it should always be. But it is nice to see folks using common sense and not abusing ERs as clinics.

I am in no way knocking 'alternative' medicine. There a lots of natural things you can do to try to stay healthy. I encourage y'all to pursue it while you're in good health.

Four of my kids are in the same position and also in healthcare. They are also getting nervous. They just sent out testing on four possibles from patients they have been heavily exposed to. If any come back positive they are screwed and will be in lockdown for a bit.

[donnay]

Link?

https://cordbloodaware.org/2018/01/m...helped-father/
https://nsistemcell.com/11-ways-to-s...immune-system/
https://www.stemcelltherapy.tv/how-t...system-dr-axe/
https://stemcelltherapyjacksonville....-and-covid-19/

[Created4]

https://cordbloodaware.org/2018/01/m...helped-father/
https://nsistemcell.com/11-ways-to-s...immune-system/
https://www.stemcelltherapy.tv/how-t...system-dr-axe/
https://stemcelltherapyjacksonville....-and-covid-19/

I'm familiar with stem cell therapy in general, but was wondering if you had any links where it is used for viral infections, and if they are using it anywhere currently during this time with coronavirus patients?

[tfurrh]

Chloroquine?....more like BORE-oquine.

[donnay]

I'm familiar with stem cell therapy in general, but was wondering if you had any links where it is used for viral infections, and if they are using it anywhere currently during this time with coronavirus patients?

https://stemcelltherapyjacksonville....-and-covid-19/

[Valli6]

In another month or so, I will have 'Sweet Annie' (Artemisia annua) plants growing all over my yard, which is also used to treat malaria. Wonder if it works similarly? I planted it on purpose one year, because it smells good - but it's kind of "weedy"- it drops seeds and will appear all over the garden the next year. (Easy to pull out when young, less easy to pull in late summer when it matures into a 5-6' plant.)


(How Sweet Annie affects malaria)

...Artemisinin and its derivatives are toxic to the malarial parasite at nanomolar concentrations, causing specific membrane structural changes in the erythrocyte [blood?] stage that kill the parasite. In general, the mechanism of action involves 2 steps: activation followed by alkylation. Iron activates artemisinin into a free radical through an iron-mediated cleavage. The second step, alkylation, involves the formation of covalent bonds between the artemisinin-derived free radicals and the malarial proteins...

MUCH more: https://www.drugs.com/npp/sweet-wormwood.html

ARTEMISIA ANNUA L.: THE HOPE AGAINST MALARIA AND CANCER
JORGE F.S. FERREIRA1
1 USDA-ARS, AFSRC. 1224 AIRPORT RD., BEAVER, WV 25813
https://www.ars.usda.gov/ARSUserFile...aandcancer.pdf

Side note: Artemisia annua (Sweet Annie) is related to, but a different plant from Artemisia absinthium (Wormwood) which is used to make absinthe and (I think?) gin. I have that plant too - has a different smell, borderline gross, till you get accustomed to it.

[jmdrake]

Yeah sure, just like you can go to that same pharmacy and buy toilet paper. And it needs a doctor's prescription....

If you're going to a doctor or nurse to get your IV you still have that cost. The generic version of this drug is $21 per bottle as opposed to $360 for the name brand.

See: https://www.healthwarehouse.com/solr...RoCFusQAvD_BwE

The cost for your vitamin C IV drip is.....? And no, the average person isn't going to give it to himself / herself at home.

[jmdrake]

In another month or so, I will have 'Sweet Annie' (Artemisia annua) plants growing all over my yard, which is also used to treat malaria. Wonder if it works similarly? I planted it on purpose one year, because it smells good - but it's kind of "weedy"- it drops seeds and will appear all over the garden the next year. (Easy to pull out when young, less easy to pull in late summer when it matures into a 5-6' plant.)


(How Sweet Annie affects malaria)



Side note: Artemisia annua (Sweet Annie) is related to, but a different plant from Artemisia absinthium (Wormwood) which is used to make absinthe and (I think?) gin. I have that plant too - has a different smell, borderline gross, till you get accustomed to it.

Thanks for sharing! It does seem to have antiviral properties.

https://www.ncbi.nlm.nih.gov/pubmed/16902856

Worth looking into.

[nobody's_hero]

Four of my kids are in the same position and also in healthcare. They are also getting nervous. They just sent out testing on four possibles from patients they have been heavily exposed to. If any come back positive they are screwed and will be in lockdown for a bit.

Which brings up another question, what happens when all the healthcare workers have gone into lock down? I asked my dept. manager this morning and he said, "When that happens, we're screwed."

Forgive the hyperbole but this must be how those GIs felt riding in those Higgins boats towards the shoreline on Normandy. You just accept the fact that you've already bought it and do what you can for the time being. Maybe you'll get through unscathed.

[ATruepatriot]

Which brings up another question, what happens when all the healthcare workers have gone into lock down? I asked my dept. manager this morning and he said, "When that happens, we're screwed."

Forgive the hyperbole but this must be how those GIs felt riding in those Higgins boats towards the shoreline on Normandy. You just accept the fact that you've already bought it and do what you can for the time being. Maybe you'll get through unscathed.

It's already happening, One daughter is a nurse in a pediatric clinic and she was telling us last night that they may close the clinic. The management is already calling patients telling them to stay home unless it is something extremely urgent. In the mean time now there are not enough patients coming in to justify paying the hours and staff. So the dummies are going to close it completely and refer everyone to the ER instead. This will destroy my kid's financial security. If it lasts even 4 weeks they will be living in their car homeless with 4 kids...

This has got to be the dumbest thing I have ever seen this country do yet...

[r3volution 3.0]

Very encouraging

Since it's been around forever and is already commonly used I expect they could ramp up production very quickly.

More about some studies:

Researchers and virologists in France have completed a clinical trial studying the effects of hydroxychloroquine, used to treat arthritis, malaria, and other ailments, on patients with COVID-19. Researchers treated a total of 26 coronavirus patients with the drug, including six that were given the antibiotic azithromycin, as well.

The researchers released their findings in a study published on Wednesday. The results showed that all six patients treated with hydroxychloroquine and azithromycin tested negative for the virus after six days. Of the 20 treated with just hydroxychloroquine, 57.1% tested negative for the coronavirus after six days. Just 12.5% of the control group made up of 16 other patients tested negative.

"Despite its small sample size our survey shows that hydroxychloroquine treatment is significantly associated with viral load reduction/disappearance in COVID-19 patients and its effect is reinforced by azithromycin," the study said.

Didier Raoult, an infectious disease expert from l’Institut Hospitalo-Universitaire in Marseille, led the research team that conducted the study. Gregory Rigano, an adviser to the Stanford University School of Medicine SPARK Translational Research Program, is leading a program based on Raoult’s results to study the effects of hydroxychloroquine on treating COVID-19, the disease caused by the coronavirus.

https://www.washingtonexaminer.com/n...irus-treatment

[Dr.3D]

Very encouraging

Since it's been around forever and is already commonly used I expect they could ramp up production very quickly.

More about some studies:



https://www.washingtonexaminer.com/n...irus-treatment

Bayer donates chloroquine to U.S., to seek emergency use as COVID-19 treatment
https://www.marketwatch.com/story/ba...ent-2020-03-19

U.S. listed shares of Bayer AG BAYRY, +0.97% rose 3% in trading on Thursday afternoon after it said it had donated three million tablets of Resochin, a chloroquine product, to the U.S. The German drugmaker said that it is seeking an emergency use authorization for the drug in the U.S., where it is not approved. Health care providers in countries like China and France have been using chloroquine-based therapies to treat COVID-19 patients as there are no proven treatments for the disease. At a news conference on Thursday, President Donald Trump talked up use of the antimalaria drug to treat patients who have the novel coronavirus, and FDA commissioner Stephen Hahn said that while chloroquine has been approved for other indications, it would still need to go through clinical trials. Bayer's stock is down 34% year-to-date, while the S&P 500 SPX, +0.47% has dropped 25%.

[Matt Collins]

Interesting... the CBP officer checking me back in to the country tonight mentioned the exact same thing to me.

[Anti Federalist]

Cheap, easy to produce, effective, no current patent...now I know why the medical talking heads were all pooh poohing the idea.

I had a scrip of this stuff laying around from the last time I went to Africa...damn

[Danke]

I'm flying out Sunday, come with me.

[Anti Federalist]

Seriously? You think they are just going to give it away for free?? No, our tax dollars will pay for its production and distribution...

As already posted, Bayer did just that.

Three million doses as a matter of fact, they gave away for free.

I'm not a fan of big pharma, but this runs counter to the norm...the norm would be to ignore this drug and insist that everybody take the new drug that just handily came out and instead of costing a buck a pill costs $5000 a dose.

[Danke]

Danke doesn't fear coronavirus, coronavirus fears Danke.

[r3volution 3.0]

As already posted, Bayer did just that.

Three million doses as a matter of fact, they gave away for free.

I'm not a fan of big pharma, but this runs counter to the norm...the norm would be to ignore this drug and insist that everybody take the new drug that just handily came out and instead of costing a buck a pill costs $5000 a dose.

I'm also pleasantly surprised.

They must have accidentally appointed a CEO with a soul.

[dannno]

I'm also pleasantly surprised.

They must have accidentally appointed a CEO with a soul.

Ya, his name is Trump.

[r3volution 3.0]

Ya, his name is Trump.

LOL

[Anti Federalist]

I'm also pleasantly surprised.

They must have accidentally appointed a CEO with a soul.

Yah, he'll be quietly fired after all this blows over.

[Anti Federalist]

Thank you for your service.

Seriously.

I'm not at liberty to give too much information because of HIPPA restrictions, but we have some high-probability COVID-19 patients at the small rural hospital where I work. The unfortunate thing about it is that the few testing kits we have must be sent out and may take days to get results. By the time their test results come back, I might already be showing symptoms, because I have been involved in their care.

In their current condition, I can assure you that these patients are not concerned with potential side effects of Plaquenil (hydroxychloroquine). One patient was placed on a ventilator early this week and another was intubated as I left work this morning. They are both older than 70. Both at high-risk. One may not live.

Modern medicine is a lot about risks versus benefits. If these were young patients with mild symptoms who weren't coughing so severely they can't take a breath and running high fevers (I'm talking >104F, which is very significant for seniors because the elderly usually do not run high fever), I'd say it might be worth worrying about things like long term kidney damage or heart failure.

IV vitamin bags will not do these patients any good at this point. While I am all about natural remedies over pushing pills on people, there comes a point where you have to honestly say what will be most effective in the moment. There are a lot of doctors out there who are more about running tests for big pharma than actually practicing the skills that doctors have utilized long before Pfizer or Glaxo-Smith-Kline started packaging pills.

The scary thing for me is that as a healthcare worker in the ER who is required to come in contact with these patients . . . our gowns, gloves, and simple mask/respirator supplies are running low. What's worse, is that when the PPE gets wet, it loses effectiveness. Anyone who has ever worn these things knows that the materials do NOT breathe, and you WILL sweat. A LOT. I'm more than a little nervous right now that I might be personally in for a rough few weeks, but like I said, I won't know until symptoms show. If I stop posting in the next few days, y'all can assume what happened.

One good thing about this whole thing, is that we are seeing a lot less 'nonsense' cases in the emergency department. People are heeding warnings and not going to hospitals unless having a true emergency that cannot wait. That's really the way it should always be. But it is nice to see folks using common sense and not abusing ERs as clinics.

I am in no way knocking 'alternative' medicine. There a lots of natural things you can do to try to stay healthy. I encourage y'all to pursue it while you're in good health.

[r3volution 3.0]

^^^Agreed

I can't imagine what it's like being in medicine right now.

[presence]

Thread: Promising Clinical Trial Hydroxychloroquine + Zithromax

[Michael Landon]

Anyone have an update on the clinical trials in New York that started Tuesday?

- ML

[donnay]

[Brian4Liberty]

https://abcnews.go.com/Health/chloro...ry?id=69664561

[I]What do malaria and COVID-19 have in common? On the surface, not much. But according to early research, an old malaria drug called chloroquine might also work for the new coronavirus.

Could a decades-old malaria drug work to treat COVID-19? Elon Musk seems to think so, recently tweeting that it "might be worth considering chloroquine" for COVID-19. Although data are spare, studies so far seem to back up the billionaire entrepreneur’s suggestion.

Chloroquine, or hydroxychloroquine, has been used to treat malaria since 1944. It can be given before exposure to malaria to prevent infection, and it can also be given as treatment afterward.

...

Remember when no one believed that this would work?

Anyone have an update on the clinical trials in New York that started Tuesday?

- ML

I believe they are promising.