Coronaviruses primarily infect the upper respiratory and gastrointestinal tract of
mammals and birds. Seven different currently known strains of coronaviruses infect humans. Coronaviruses are believed to cause a significant percentage of all common colds in human adults and children. Coronaviruses cause colds with major symptoms, e.g. fever, throat swollen adenoids, in humans primarily in the winter and early spring seasons.[5] Coronaviruses can cause pneumonia, either direct viral pneumonia or a secondary bacterial pneumonia, and bronchitis, either direct viral bronchitis or a secondary bacterial bronchitis.[6]
The much publicized human coronavirus discovered in 2003, SARS-CoV which causes severe acute respiratory syndrome (SARS), has a unique pathogenesis because it causes both upper and lower respiratory tract infections.[6] The significance and economic impact of coronaviruses as causative agents of the common cold are hard to assess because, unlike rhinoviruses (another common cold virus), human coronaviruses are difficult to grow in the laboratory.
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There are seven known strains of human coronaviruses:
1. Human coronavirus 229E
2. Human coronavirus OC43
3.
SARS-CoV
4. Human coronavirus NL63 (HCoV-NL63, New Haven coronavirus)
5. Human coronavirus HKU1
6. Middle East respiratory syndrome coronavirus (
MERS-CoV), previously known as Novel coronavirus 2012 and HCoV-EMC.
7.
Wuhan coronavirus (2019-nCoV),[14][15] also known as novel coronavirus 2019/2020 (Wuhan pneumonia).[16]
Following the high-profile publicity of SARS outbreaks, there has been a renewed interest in coronaviruses among virologists. For many years, scientists knew about only two human coronaviruses (HCoV-229E and HCoV-OC43). The discovery of SARS-CoV added a third human coronavirus.
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More:
https://en.m.wikipedia.org/wiki/Coronavirus
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