2011 March - Security forces shoot dead protestors in southern city of Deraa demanding release of political prisoners, triggering violent unrest that steadily spread nationwide over the following months.
President Assad announces conciliatory measures, releasing dozens of political prisoners, dismissing government, lifting 48-year-old state of emergency.
2011 May - Army tanks enter Deraa, Banyas, Homs and suburbs of Damascus in an effort to crush anti-regime protests. US and European Union tighten sanctions.
2011 June - The IAEA nuclear watchdog decides to report Syria to the UN Security Council over its alleged covert nuclear programme reactor programme. The structure housing the alleged reactor was destroyed in an Israeli air raid in 2007.
Opposition organises
2011 July - President Assad sacks the governor of the northern province of Hama after mass demonstration there, eventually sending in troops to restore order at the cost of scores of lives.
2011 October - New Syrian National Council says it has forged a common front of internal and exiled opposition activists.
2011 November - Arab League votes to suspend Syria, accusing it of failing to implement an Arab peace plan, and imposes sanctions.
2012 February - Government steps up the bombardment of Homs and other cities.
2012 March - UN Security Council endorses non-binding peace plan drafted by UN envoy Kofi Annan. China and Russia agree to support the plan after an earlier, tougher draft is modified.
2012 June - Turkey changes rules of engagement after Syria shoots down a Turkish plane, declaring that if Syrian troops approach Turkey's borders they will be seen as a military threat.
2012 July - Free Syria Army blows up three security chiefs in Damascus and seizes parts of the city of Aleppo in the north.
2012 August - Prime Minister Riad Hijab defects, US President Obama warns that use of chemical weapons would tilt the US towards intervention.
2012 October - Fire in Aleppo destroys much of the historic market as fighting and bomb attacks continue in various cities.
2012 November - National Coalition for Syrian Revolutionary and Opposition Forces formed in Qatar, excludes Islamist militias. Arab League stops short of full recognition.
2012 December - US, Britain, France, Turkey and Gulf states formally recognise opposition National Coalition as "legitimate representative" of Syrian people.
2013 January - Syria accuses Israel of bombing military base near Damascus, where Hezbollah was suspected of assembling a convoy of anti-aircraft missiles bound for Lebanon.
2013 September - UN weapons inspectors conclude that chemical weapons were used in an attack on the Ghouta area of Damascus in August that killed about 300 people, but do not allocate responsibility. Government allows UN to destroy chemical weapons stocks, process complete by June 2014.
2013 December - US and Britain suspend "non-lethal" support for rebels in northern Syria after reports that Islamist rebels seized bases of Western-backed Free Syrian Army.
2014 January-February - UN-brokered peace talks in Geneva fail, largely because Syrian authorities refuse to discuss a transitional government.
2014 March - Syrian Army and Hezbollah forces recapture Yabroud, the last rebel stronghold near the Lebanese border.
2014 June - Islamic State of Iraq and Syria militants declare "caliphate" in territory from Aleppo to eastern Iraqi province of Diyala.
2014 September - US and five Arab countries launch air strikes against Islamic State around Aleppo and Raqqa.
2015 January - Kurdish forces push Islamic State out of Kobane on Turkish border after four months of fighting.
2015 May - Islamic State fighters seize the ancient city of Palmyra in central Syria and proceed to destroy many monuments at pre-Islamic World Heritage site.
Jaish al-Fatah (Army of Conquest) Islamist rebel alliance takes control of Idlib Province, putting pressure on government's coastal stronghold of Latakia.
Russian intervention
2015 September - Russia carries out its first air strikes in Syria, saying they target the Islamic State group, but the West and Syrian opposition say it overwhelmingly targets anti-Assad rebels.
2015 December - Syrian Army allows rebels to evacuate remaining area of Homs, returning Syria's third-largest city to government control after four years.
2016 March - Syrian government forces retake Palmyra from Islamic State with Russian air assistance, only to be driven out again in December.
2016 August - Turkish troops cross into Syria to help rebel groups push back so-called Islamic State militants and Kurdish-led rebels from a section of the two countries' border.
2016 December - Government troops, backed by Russian air power and Iranian-sponsored militias, recapture Aleppo, the country's largest city, depriving the rebels of their last major urban stronghold.
2017 January - Russia, Iran and Turkey agree to enforce a ceasefire between the government and non-Islamist rebels, after talks between the two sides in Kazakhstan.
US intervenes
2017 April - US President Donald Trump orders a missile attack on an airbase from which Syrian government planes allegedly staged a chemical weapons attack on the rebel-held town of Khan Sheikhoun.
2017 May - US decides to arm the YPG Kurdish Popular Protection Units. These fight alongside the main opposition Syrian Democratic Forces, which captures the important Tabqa dam from Islamic State.
2017 June - US shoots down Syrian fighter jet near Raqqa after it allegedly dropped bombs near US-backed rebel Syrian Democratic Forces (SDF).
2017 July - The Lebanese militant group Hezbollah and the Syrian army launch a military operation to dislodge jihadist groups from the Arsal area, near the Lebanese-Syrian border.
Islamic State retreats
2017 October-November - The Islamic State group is driven from Raqqa, its de-facto capital in Syria, and Deir al-Zour.
2018 January - Turkey launches an assault on northern Syria to oust Kurdish rebels controlling the area around Afrin.
2018 April - Claims of a new chemical attack in Eastern Ghouta's main town of Douma prompt the US, Britain and France to carry out a wave of punitive strikes on Syrian targets.
2018 July - Syrian army recaptures almost all of the south of the country, up to the borders with Jordan and Israeli-held territory.
2018 September-December - Kurdish-led SDF forces launch offensive that reduces Islamic State territory to a tiny enclave on the Iraqi border.
2019 October - US withdraws troops from northern Syria, prompting Turkey to attack US Kurdish allies in the area.
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