GMO Baby?!? (Or, How Science Used Gene Editing To Treat Leukemia)

[angelatc]

https://www.newscientist.com/article...n-world-first/

For the first time ever, a person’s life has been saved by gene editing.

One-year-old Layla was dying from leukaemia after all conventional treatments failed. “We didn’t want to give up on our daughter, though, so we asked the doctors to try anything,” her mother Lisa said in a statement released by Great Ormond Street Hospital in London, where Layla (pictured above) was treated.

And they did. Layla’s doctors got permission to use an experimental form of gene therapy using genetically engineered immune cells from a donor. Within a month these cells had killed off all the cancerous cells in her bone marrow.

More at the link https://www.newscientist.com/article...n-world-first/

[TheTexan]

Is this a Monsanto baby?

[donnay]

Sulforaphane (from Non-GMO Broccoli and other Non-GMO cruciferous vegetables) works well.

http://journals.plos.org/plosone/art...l.pone.0051251

[angelatc]

Sulforaphane (from Non-GMO Broccoli and other Non-GMO cruciferous vegetables) works well.

http://journals.plos.org/plosone/art...l.pone.0051251

Uhm ...

One-year-old Layla was dying from leukaemia after all conventional treatments failed.

And nowhere in the study you cited is non-GM specified. Agenda much?

[Zippyjuan]

Sulforaphane (from Non-GMO Broccoli and other Non-GMO cruciferous vegetables) works well.

http://journals.plos.org/plosone/art...l.pone.0051251

Eating your broccoli is not going to help (also noting that they used a synthetic- not natural- version of the compound so it was not non-GMO). Article also does not claim that any patients were cured by it.

indicate that a therapeutic concentration of SF cannot be reached through the dietary consumption of cruciferous vegetables.

although we did not observe significant differences in survival

[Natural Citizen]

Relevant threads where we have discussed this ...

http://www.ronpaulforums.com/showthread.php?473448-Chinese-researchers-modify-human-genome&p=5851366&viewfull=1#post5851366

http://www.ronpaulforums.com/showthr...=1#post5859471

http://www.ronpaulforums.com/showthr...=1#post5816406

[Natural Citizen]

Uhm ...



And nowhere in the study you cited is non-GM specified. Agenda much?

Heh. "Genetic Editing" language, we've been expecting to come up in the latest PR campaign. Is just a slick way to avoid any oversight where there truly does need to be some. I suppose we understand that "genetic editing" is not transgenic.

angela, I'm going to bookmark your thread. I'm curious to see where you intend to go with this.

I suppose that you know that I won't let you.

[donnay]

One-year-old Layla was dying from leukaemia after all conventional treatments failed.

One-year-old Layla was dying from leukaemia after all conventional treatments failed.

One-year-old Layla was dying from leukaemia after all conventional treatments failed.

[Zippyjuan]

Yes, we read that. Does it mean that all conventional treatments always fail? (noting that your broccoli "cure" also failed to cure anybody according to the article).

[donnay]

Yes, we read that. Does it mean that all conventional treatments always fail? (noting that your broccoli "cure" also failed to cure anybody according to the article).

Conventional medicine is Big pHARMa. Alternative medicine is rarely approved by the medical mafia-- the unholy trinity of AMA (American Medical Association), FDA (Food and Drug Administration), and Big pHARMa. Conventional medicine does not cure--it treats.

Sulforaphane in Broccoli kills Leukemia cancer cells in the study above--it's not an article.

[Zippyjuan]

Isn't the FDA in charge of broccoli? (again noting that the study used a synthetic chemical and did not report curing anybody- unless you can show where it does and what percent were cured).

Chemicals

Synthetic DL-Sulforaphane (SF) was purchased from Sigma-Aldrich (St. Louis, MO) and LKT Laboratories (St. Paul, MN) for both the in vitro and in vivo studies. SF was dissolved in dimethyl sulfoxide (DMSO) to generate a 40 mM stock concentration and stored at −20°C. SF was diluted to the specified final concentration in RPMI-1640 medium supplemented with 10% fetal bovine serum (FBS). The volume of DMSO was less than 0.1% of the total volume, and the identical dilution of DMSO in culture medium was used as the vehicle control. S-(N-Methylsulfinylbutylthiocarbamoyl)-glutathione (SF-glutathione), S-(N-Methylsulfinylbutylthiocarbamoyl)-L-cysteine (SF-cysteine), and N-Acetyl-S-(N-Methylsulfinylbutylthiocarbamoyl)-L-cysteine (SF-NAC) were obtained from LKT Laboratories.

[donnay]

Isn't the FDA in charge of broccoli? (again noting that the study used a synthetic chemical and did not report curing anybody- unless you can show where it does and what percent were cured).

Researchers used a concentrated form of this compound on human-derived leukemic cancer cells. Since acute lymphoblastic leukemia is a type of cancer of the white blood cells most common in children, for their study the researchers used leukemic cancer cells from pediatric patients.

“Sulforaphane is a natural product. However, what we used in this study is a concentrated purified form. So while eating cruciferous vegetables is good for you, it will not have the same effect as what we saw in the lab,” said Dr. Daniel Lacorazza, appointed Assistant Professor of Pathology and Immunology at the College. He also said that the cure rate is about 80%, but some children don’t respond to the treatment. For those difficult cases, he called for alternative treatments.

http://www.dietoflife.com/compound-i....VZ7KLhx2.dpuf

[Zippyjuan]

Not bad. How does that compare with more "traditional" treatments?

http://www.cancer.net/cancer-types/l...cll/statistics

Overall, the combined five-year survival rate of people with all stages of CLL is about 84%.

[angelatc]

Not bad. How does that compare with more "traditional" treatments?

http://www.cancer.net/cancer-types/l...cll/statistics

Its too soon to know if the baby will live past the 5 year benchmark. But the technology that saved her life was discovered here in the USA, as part of some basic crop research here in Iowa.

http://www.sciencemag.org/content/32...=GOOGLESCHOLAR
http://www.tsl.ac.uk/news/matt-mosco...mia-treatment/

Dr Moscou, whose research centres on how some plants are susceptible to diseases while others are not, developed a new genome editing technique as a side interest to his research into plant disease immunity at his former institute, Iowa State University.

Now, that technology has been used to precisely edit the genes in bone marrow tissue that was removed from the patient, in order that it can be reintroduced back into the patient and promote the establishment of a second bone marrow transplant.

[jmdrake]

https://www.newscientist.com/article...n-world-first/



More at the link https://www.newscientist.com/article...n-world-first/

Great. Wonderful. I'm not sure what this has to do with the GMO food debate unless....

[jmdrake]

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