Man's Mutated Polio Virus Remains In Gut For 30 Years
A man's polio vaccine mutated in his gut into a much more virulent strain of the virus and has caused concern for eradication efforts.
A 29-year-old British man made medical history after doctors found that the polio vaccine he received as an infant mutated into a virulent strain which lived in his gut for nearly 30 years. Although the man has no symptoms of the virus, he has been shedding a highly contagious form of the virus in his stool. In a recent study on the case, researchers called the discovery a "worrisome new development in the polio end game" and expressed concern that his case may not be isolated.
The unnamed British man received the mandatory full course of oral vaccinations of the weakened polio virus in the form of a sugar cube at five, seven, and 12 months, followed by a booster at seven. However, according to The Guardian, a non-related health condition suppressed his immune system and prevented his body from destroying the virus. As a result, the polio virus was able to live inside of his gut for his entire life and was present in a large quantity in his stool.
Viral shedding refers to the presence of a virus in body secretions which hold the potential for disease transmission and transfer. Although this behavior has been often noted, most commonly in the case of the herpes virus, this case marks the longest period of viral shedding that doctors have ever observed.
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