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Thread: Magic Mushrooms Create a Hyperconnected Brain

  1. #1

    Magic Mushrooms Create a Hyperconnected Brain

    I want to try these one day.

    Magic mushrooms may give users trippy experiences by creating a hyperconnected brain.

    The active ingredient in the psychedelic drug, psilocybin, seems to completely disrupt the normal communication networks in the brain, by connecting "brain regions that don't normally talk together," said study co-author Paul Expert, a physicist at King's College London.

    The research, which was published today (Oct. 28) in the Journal of the Royal Society Interface, is part of a larger effort to understand how psychedelic drugs work, in the hopes that they could one day be used by psychiatrists — in carefully controlled settings — to treat conditions such as depression, Expert said. [Trippy Tales: The History of 8 Hallucinogens]

    Magic mushrooms

    Psilocybin, the active ingredient in magic mushrooms, is best known for triggering vivid hallucinations. It can make colors seem oversaturated and dissolve the boundaries between objects.

    But the drug also seems to have more long-lasting effects. Many people report intensely spiritual experiences while taking the drug, and some studies even suggest that one transcendent trip can alter people's personalities on a long-term basis, making those individuals more open to new experiences and more appreciative of art, curiosity and emotion.

    People who experiment with psilocybin "report it as one of the most profound experiences they've had in their lives, even comparing it to the birth of their children," Expert told Live Science.


    Making connections

    Scientists have long known that psilocybin binds to a receptor in the brain for serotonin, a brain chemical that plays a role in mood, appetite and sleep, but exactly how the drug transforms the whole brain's pattern of communication isn't clear.

    In past work, Expert's colleagues had found that psilocybin spurred the brain into a more dreamlike state, and that the drug decreased brain activity.

    In the current study, the team used functional magnetic resonance imaging (fMRI) to scan the brain activity of 15 healthy volunteers — once after they had taken a placebo, and once after they took the hallucinogen psilocybin. (The team chose only people who had reported past positive experiences with magic mushrooms to prevent them from panicking inside the claustrophobic MRI machines.)

    The team then compared the brain activity of the individuals on and off the drug, and created a map of connections between different brain regions.

    Psilocybin dramatically transformed the participants' brain organization, Expert said. With the drug, normally unconnected brain regions showed brain activity that was synchronized tightly in time. That suggested the drug was stimulating long-range connections the brain normally wouldn't make. After the drug wore off, brain activity went back to normal.

    Drug's effect

    Psilocybin may create a brain state akin to synesthesia, a sensory effect in which one sense stimulus (such as a number) always gets paired in the brain with another (such as a color or a sound), the researchers wrote in the paper. People with synesthesia may see certain colors when they hear music, or always see the number 3 in yellow, for instance, Expert said.

    The findings could help scientists who are studying the drug as a potential treatment for depression, Expert said. Past work has found that people tend to be happier even after using psilocybin just once, but scientists would need to get a much better picture of how the drug impacts the brain before using psilocybin to treat depression, Expert said.

    The research could ultimately also help answer bigger questions of the mind, like how people construct a sense of self.

    "Through studies such as these we can really begin to tackle the questions of how we achieve coherent experiences of ourselves in the world around us, and understand what makes this break down," said Mitul Mehta, a psychopharmacology researcher at King's College London, who was not involved in the study.

    http://news.yahoo.com/magic-mushroom...172648890.html



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  3. #2
    Good to read pro-psychedelic press!


  4. #3
    Good article, gonna save this.
    Quote Originally Posted by Sister Miriam Godwinson View Post
    We Must Dissent.

  5. #4

  6. #5
    Quote Originally Posted by specsaregood View Post
    Very interesting!

  7. #6
    In the current study, the team used functional magnetic resonance imaging (fMRI) to scan the brain activity of 15 healthy volunteers
    Why do I always miss these volunteer opportunities?
    "And now that the legislators and do-gooders have so futilely inflicted so many systems upon society, may they finally end where they should have begun: May they reject all systems, and try liberty; for liberty is an acknowledgment of faith in God and His works." - Bastiat

    "It is difficult to free fools from the chains they revere." - Voltaire

  8. #7
    Just make sure you're in a positive state of mind and around people of the same. Drugs amplify your current underlying emotions. If you're a happy, no worries person you'll have an excellent experience. If you're depressed or have fear issues those will be amplified and you may not like what you see.

  9. #8



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  11. #9
    If you think that's cool you should hear what people think DMT does..

    Shrooms are good stuff.
    "He's talkin' to his gut like it's a person!!" -me
    "dumpster diving isn't professional." - angelatc
    "You don't need a medical degree to spot obvious bullshit, that's actually a separate skill." -Scott Adams
    "When you are divided, and angry, and controlled, you target those 'different' from you, not those responsible [controllers]" -Q

    "Each of us must choose which course of action we should take: education, conventional political action, or even peaceful civil disobedience to bring about necessary changes. But let it not be said that we did nothing." - Ron Paul

    "Paul said "the wave of the future" is a coalition of anti-authoritarian progressive Democrats and libertarian Republicans in Congress opposed to domestic surveillance, opposed to starting new wars and in favor of ending the so-called War on Drugs."

  12. #10
    Quote Originally Posted by dannno View Post
    Shrooms are good stuff.
    Don't ever slide the wrong weight on a set of tri-beams when you're drunkenly measuring your own dose of dried shrooms....

  13. #11
    Quote Originally Posted by tod evans View Post
    Don't ever slide the wrong weight on a set of tri-beams when you're drunkenly measuring your own dose of dried shrooms....
    lol ya I tend not to mix alcohol with any of the following:

    mushrooms
    lsd
    MDMA
    DMT
    "He's talkin' to his gut like it's a person!!" -me
    "dumpster diving isn't professional." - angelatc
    "You don't need a medical degree to spot obvious bullshit, that's actually a separate skill." -Scott Adams
    "When you are divided, and angry, and controlled, you target those 'different' from you, not those responsible [controllers]" -Q

    "Each of us must choose which course of action we should take: education, conventional political action, or even peaceful civil disobedience to bring about necessary changes. But let it not be said that we did nothing." - Ron Paul

    "Paul said "the wave of the future" is a coalition of anti-authoritarian progressive Democrats and libertarian Republicans in Congress opposed to domestic surveillance, opposed to starting new wars and in favor of ending the so-called War on Drugs."

  14. #12
    Quote Originally Posted by dannno View Post
    lol ya I tend not to mix alcohol with any of the following:

    mushrooms
    lsd
    MDMA
    DMT
    Some friends and I purchased a quantity of dried and pulverised shrooms so it wasn't as simple as "12 is too many", it was mixing a powder with whiskey...

    I vaguely remember lying in a snowdrift staring at the night sky contemplating the universe.....

  15. #13
    Quote Originally Posted by tod evans View Post
    Some friends and I purchased a quantity of dried and pulverised shrooms so it wasn't as simple as "12 is too many", it was mixing a powder with whiskey...

    I vaguely remember lying in a snowdrift staring at the night sky contemplating the universe.....
    I made a similar miscalculation that left me in a cave in Big South Fork not knowing which way was up.

    I want to try these one day.
    Seek and ye shall find. Seriously. I've noticed that any time I wanted to find some shrooms they seemed to find me somehow.

  16. #14
    Quote Originally Posted by tod evans View Post
    Some friends and I purchased a quantity of dried and pulverised shrooms so it wasn't as simple as "12 is too many", it was mixing a powder with whiskey...

    I vaguely remember lying in a snowdrift staring at the night sky contemplating the universe.....

    Quote Originally Posted by FunkBuddha View Post
    I made a similar miscalculation that left me in a cave in Big South Fork not knowing which way was up.



    Seek and ye shall find. Seriously. I've noticed that any time I wanted to find some shrooms they seemed to find me somehow.

    Hopefully they'll find me one day.

  17. #15
    Quote Originally Posted by Suzanimal View Post
    I want to try these one day.
    Thought criminal! You will get Ritalin and Prozac and you will like it!
    I too have been a close observer of the doings of the Bank of the United States...When you won, you divided the profits amongst you, and when you lost, you charged it to the bank...You are a den of vipers and thieves. I have determined to rout you out, and by the Eternal, I will rout you out!

    Andrew Jackson, 1834

  18. #16
    Quote Originally Posted by Suzanimal View Post
    Quote Originally Posted by FunkBuddha View Post
    Seek and ye shall find. Seriously. I've noticed that any time I wanted to find some shrooms they seemed to find me somehow.

    Hopefully they'll find me one day.
    Next time you hear about Phish, or the Grateful dead or phil lesh coming to your area. Go out tailgating at the show (you don't have to bother going into the show). hit shakedown street and within a few minutes somebody will stroll buy advertising them for sale.



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  20. #17
    Interesting...

    11 Odd Facts About 'Magic' Mushrooms

    At first glance, Psilocybe cubensis doesn't look particularly magical. In fact, the scientific name of this little brown-and-white mushroom roughly translates to "bald head," befitting the fungus's rather mild-mannered appearance. But those who have ingested a dose of P. cubensis say it changes the user's world.

    The mushroom is one of more than 100 species that contain compounds called psilocybin and psilocin, which are psychoactive and cause hallucinations, euphoria and other trippy symptoms. These "magic mushrooms" have long been used in Central American religious ceremonies, and are now part of the black market in drugs in the United States and many other countries, where they are considered a controlled substance.

    How does a modest little mushroom upend the brain so thoroughly? Read on for the strange secrets of 'shrooms.

    1. Mushrooms hyperconnect the brain

    An artist's image shows neurons sending signals within the human brain.
    The compounds in psilocybin mushrooms may give users a "mind-melting" feeling, but in fact, the drug does just the opposite — psilocybin actually boosts the brain's connectivity, according to an October 2014 study. Researchers at King's College London asked 15 volunteers undergo brain scanning by a functional magnetic resonance imaging (fMRI) machine. They did so once after ingesting a dose of magic mushrooms, and once after taking a placebo. The resulting brain connectivity maps showed that, while under the influence of the drug, the brain synchronizes activity among areas that would not normally be connected. This alteration in activity could explain the dreamy state that 'shroom users report experiencing after taking the drug, the researchers said.

    2. Slow it down

    'Shrooms act in other strange ways upon the brain. Psilocybin works by binding to receptors for the neurotransmitter serotonin. Although it's not clear exactly how this binding affects the brain, studies have found that the drug has other brain-communication-related effects in addition to increased synchronicity.

    In one study, brain imaging of volunteers who took psilocybin revealed decreased activity in information-transfer areas such as the thalamus, a structure deep in the middle of the brain. Slowing down the activity in areas such as the thalamus may allow information to travel more freely throughout the brain, because that region is a gatekeeper that usually limits connections, according to the researchers from Imperial College London.

    3. Magic mushrooms go way back

    Central Americans were using psilocybin mushrooms before Europeans landed on the New World's shores; the fantastical fungi grow well in subtropical and tropical environments. But how far back were humans tripping on magic mushrooms?

    It's not an easy question to answer, but a 1992 paper in the short-lived journal, "Integration: Journal of Mind-Moving Plants and Culture," argued that rock art in the Sahara dating back 9,000 years depicts hallucinogenic mushrooms. The art in question shows masked figures holding mushroomlike objects. Other drawings show mushrooms positioned behind anthropomorphic figures — possibly a nod to the fact that mushrooms grow in dung. (The mushroom figures have also been interpreted as flowers, arrows or other plant matter, however, so it remains an open question whether the people who lived in the ancient Sahara used 'shrooms.)

    4. Magic mushrooms explain Santa … maybe

    Amanita muscaria mushrooms
    On the subject of myth, settle in for a less-than-innocent tale of Christmas cheer. According to Sierra College anthropologist John Rush, magic mushrooms explain why kids wait for a flying elf to bring them presents on Dec. 25.

    Rush said that Siberian shamans used to bring gifts of hallucinogenic mushrooms to households each winter. Reindeer were the "spirit animals" of these shaman, and ingesting mushrooms might just convince a hallucinating tribe member that those animals could fly. Plus, Santa's red-and-white suit looks suspiciously like the colors of the mushroom species Amanita muscaria, which grows — wait for it — under evergreen trees. However, this species is toxic to people. [8 Ways Magic Mushrooms Gave Us Christmas]

    Feeling like you've just taken a bad trip? Not to worry. Not all anthropologists are sold on the hallucinogen-Christmas connection. But still, as Carl Ruck, a classicist at Boston University, told Live Science in 2012: "At first glance, one thinks it's ridiculous, but it's not."

    5. 'Shrooms may change people for good

    Psychologists say that few things can truly alter someone's personality in adulthood, but magic mushrooms may be one of those things.

    A 2011 study found that after one dose of psilocybin, people became more open to new experiences for at least 14 months, a shockingly stable change. People with open personalities are more creative and more appreciative of art, and they value novelty and emotion.

    The reason for the change seems to be psilocybin's effects on emotions. People describe mushroom trips as extremely profound experiences, and report feelings of joy and connectedness to others and to the world around them. These transcendent experiences appear to linger. (In the experiments, the researchers took great pains to assure their participants did not experience "bad trips," as some people respond to psilocybin with panic, nausea and vomiting. Volunteers were kept safe in a room with peaceful music and calming surroundings.)

    6. Mushrooms kill fear

    Another strange side effect of magic mushrooms: They destroy fear. A 2013 study in mice found that when dosed with psilocybin, the animals became less likely to freeze up when they heard a noise they had learned to associate with a painful electric shock. Mice that were not given the drug also gradually relaxed around the noise, but it took longer.

    The mice were given a low dose of psilocybin, and the researchers said they hope this animal study will inspire more work on how mushrooms might be used to treat mental health problems in people. For example, small doses of psilocybin could be explored as a way to treat post-traumatic stress disorder, the researchers said.

    7. They make their own wind

    Mushrooms don't just exist to get people high, of course; they have their own lives. And part of that life is reproduction. Like other fungi, mushrooms reproduce via spores, which travel the breeze to find a new place to grow.

    But mushrooms often live in sheltered areas on forested floors, where the wind doesn't blow. To solve the problem of spreading their spores, some 'shrooms (including the hallucinogenic Amanita muscaria) create their own wind. To do this, the fungi increase the rate that water evaporates off of their surfaces, placing water vapor in the air immediately around them. This water vapor, along with the cool air created by evaporation, works to lift spores. Together, these two forces can lift the spores up to 4 inches (10 centimeters) above the mushroom, according to a presentation at the 2013 meeting of the American Physical Society's Division of Fluid Dynamics.

    8. Many mushrooms

    Scientists found a species of gilled mushroom in the northwestern United States submerged in the clear, cold, flowing waters of the upper Rogue River in Oregon. What makes Psathyrella aquatica distinct, and a member of this year's top 10, is that it was o
    At least 144 species of mushroom contain the psychoactive ingredient psilocybin, according to a 2005 review in the International Journal of Medicinal Mushrooms. Latin America and the Caribbean are home to more than 50 species, and Mexico alone has 53. There are 22 species of magic mushroom in North America, 16 in Europe, 19 in Australia and the Pacific island region, 15 in Asia, and a mere four in Africa.

    9. Experimenting with 'shrooms

    Recently, researchers have begun to experiment with psilocybin as a potential treatment for depression, anxiety and other mental disorders. This line of research was frozen for decades and is still difficult to pursue, given psilocybin's status as a Schedule I substance. This means the drug is classified by the Drug Enforcement Administration (DEA) as having no accepted medical use and a high potential for abuse.

    In the past, though, psilocybin and other hallucinogenic drugs were at the center of a thriving research program. During the 1960s, for example, Harvard psychologist Timothy Leary and his colleagues ran a series of experiments with magic mushrooms called the Harvard Psilocybin Project. Among the most famous was the Marsh Chapel Experiment, in which volunteers were given either psilocybin or a placebo before a church service in the chapel. Those who got psilocybin were more likely to report a mystical spiritual experience. A 25-year follow-up in 1991 found that participants who got the psilocybin remembered feeling even more unity and sacredness than they said they'd felt six months after the fact. Many described the experience as life altering.

    "It left me with a completely unquestioned certainty that there is an environment bigger than the one I'm conscious of," one told the researchers in 1991. "I have my own interpretation of what that is, but it went from a theoretical proposition to an experiential one. … Somehow, my life has been different knowing that there is something out there."

    10. The counterculture cultivator

    Leary's psychedelic experiments are part of hippie lore, but the man who did the most to bring magic mushrooms to mainstream U.S. drug culture was a writer and ethnobotanist named Terence McKenna. He had been experimenting with psychedelics since his teen years, but it wasn't until a trip to the Amazon in 1971 that he discovered psilocybin mushrooms — fields of them, according to a 2000 profile in Wired magazine.

    In 1976, McKenna and his brother published "Psilocybin: Magic Mushroom Grower's Guide," a manual for cultivating psilocybin mushrooms at home. "What is described is only slightly more complicated than canning or making jelly," McKenna wrote in the foreword to the book.

    11. Animals feel the effects

    Psilocybin 'shrooms grow in the wild, so it's perhaps inevitable that nonhuman animals have sampled these trippy fungi. In 2010, the British tabloids were abuzz with reports that three pygmy goats at an animal sanctuary run by 1960s TV actress Alexandra Bastedo had gotten into some wild magic mushrooms. The goats reportedly acted lethargic, vomited and staggered around, taking two days to fully recover.

    Siberian reindeer also have a taste for magic mushrooms, according to a 2009 BBC nature documentary. It's unclear whether the reindeer feel the effects, but Siberian mystics would sometimes drink the urine from deer that had ingested mushrooms in order to get a hallucinogenic experience for religious rituals.

    http://www.livescience.com/48704-odd...41129_35444727

  21. #18
    something to listen to for those 10 twisted hours that will simultaneously feel like 5 minutes and 500 years.


  22. #19
    "Part of what psychedelics do is they decondition you from cultural values. This is what makes it such a political hot potato. Since all culture is a kind of con game, the most dangerous candy you can hand out is one which causes people to start questioning the rules of the game.”
    – Terence McKenna

  23. #20
    Thought that was old news.

    LSD does the same 'hyperconnectivity' trick. But given a choice between the two, especially if you're a first timer, go the natural route and choose shrooms.
    Quote Originally Posted by Swordsmyth View Post
    You only want the freedoms that will undermine the nation and lead to the destruction of liberty.

  24. #21
    http://www.amazon.com/Psilocybin-Sol...cybin+solution

    Excellent book on the topic, available on kindle. It blew my mind so much I looked up the author and sent him a big long philosophical email and he actually replied and now were friends on Facebook.

    Edit: I have never tried psilocybin mushrooms, but like suzanimal I am interested
    I too have been a close observer of the doings of the Bank of the United States...When you won, you divided the profits amongst you, and when you lost, you charged it to the bank...You are a den of vipers and thieves. I have determined to rout you out, and by the Eternal, I will rout you out!

    Andrew Jackson, 1834

  25. #22
    Quote Originally Posted by dannno View Post
    If you think that's cool you should hear what people think DMT does..
    Quote Originally Posted by acptulsa
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  26. #23
    While searching my closet for a missing Christmas gift, I found a sealed baggie of shrooms that I had completely forgotten about, they must be 7 years old or so.... so now I'm left wondering if they are still good to go and if I should find a time to eat them...

  27. #24
    Quote Originally Posted by ctiger2 View Post
    Just make sure you're in a positive state of mind and around people of the same. Drugs amplify your current underlying emotions. If you're a happy, no worries person you'll have an excellent experience. If you're depressed or have fear issues those will be amplified and you may not like what you see.
    I knew people in college who did shrooms. They all had their bad trips. One guy tried them for the first time and pretty much lost it, and his "friends" didn't help him much. They locked him outside. He ended up in the mental ward (psychiatric hold), and was pretty messed up. He was in the reserves, so he got in trouble with them too. Schrooms aren't for everyone.
    "Foreign aid is taking money from the poor people of a rich country, and giving it to the rich people of a poor country." - Ron Paul
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    The views and opinions expressed here are solely my own, and do not represent this forum or any other entities or persons.



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  29. #25
    Quote Originally Posted by specsaregood View Post
    While searching my closet for a missing Christmas gift, I found a sealed baggie of shrooms that I had completely forgotten about, they must be 7 years old or so.... so now I'm left wondering if they are still good to go and if I should find a time to eat them...
    I wouldn't hesitate because of age, if they're dried and sealed they should be good...

  30. #26
    Grow them yourself. More rewarding.

  31. #27
    Quote Originally Posted by kfarnan View Post
    Grow them yourself. More rewarding.
    He has a kid.

  32. #28
    Quote Originally Posted by Brian4Liberty View Post
    I knew people in college who did shrooms. They all had their bad trips. One guy tried them for the first time and pretty much lost it, and his "friends" didn't help him much. They locked him outside. He ended up in the mental ward (psychiatric hold), and was pretty messed up. He was in the reserves, so he got in trouble with them too. Schrooms aren't for everyone.
    It's not so much about the person as the physical location. I don't like doing them at home, I don't like doing them in the city, I don't like doing them around a lot of people. The best place is a 2 day+ hike from civilization in the forest or desert. The next best place is driving somewhere that is at least a 4 or 5 hour hike from civilization. The next best place after that is just somewhere that is not in civilization. The more beautiful the wilderness area you can find the better.

    What I'm saying, and I think you will agree with me here, is that if your friend was a 2 day hike from civilization when he took the shrooms he would not have ended up in the mental ward. He would have come out all the better for it.

    if you have some cool friends, or are a bit experienced, doing mushrooms at certain types of hippie oriented electronic music festivals is pretty good too.. But lsd seems to work well for those also.
    Last edited by dannno; 12-24-2016 at 03:39 PM.
    "He's talkin' to his gut like it's a person!!" -me
    "dumpster diving isn't professional." - angelatc
    "You don't need a medical degree to spot obvious bullshit, that's actually a separate skill." -Scott Adams
    "When you are divided, and angry, and controlled, you target those 'different' from you, not those responsible [controllers]" -Q

    "Each of us must choose which course of action we should take: education, conventional political action, or even peaceful civil disobedience to bring about necessary changes. But let it not be said that we did nothing." - Ron Paul

    "Paul said "the wave of the future" is a coalition of anti-authoritarian progressive Democrats and libertarian Republicans in Congress opposed to domestic surveillance, opposed to starting new wars and in favor of ending the so-called War on Drugs."

  33. #29
    Quote Originally Posted by tod evans View Post
    He has a kid.
    it's fun to grow anything.

  34. #30
    Quote Originally Posted by kfarnan View Post
    it's fun to grow anything.
    Of course it is but when a man has a family he's gotta weigh the risks.

    I've done $#@! I won't ever talk about...............................before my son was born.



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