'Do you want a toxic antibiotic and to end up on dialysis,
or would you prefer to have a limb amputated?'
http://www.usatoday.com/story/news/nation/2013/03/05/superbugs-infections-hospitals/1965133/
A new family of antibiotic-resistant bacteria, known as CRE,
is raising concerns across the medical community
because of its ability to cause infections that defy even the strongest antibiotics.
The antibiotic resistance is spread by mobile pieces of DNA
that can move between different species of bacteria,
creating new, drug-defying bugs
[]
the country could be entering the beginning of the "post-antibiotic era."
[]
There is little chance that an effective drug to kill CRE bacteria
will be produced in the coming years.
http://en.wikipedia.org/wiki/Carbape...robacteriaceae
Carbapenem-resistant enterobacteriaceae (CRE)
Death rates of up to 50%
http://www.medicalnewstoday.com/releases/257019.phpPatients who tested positive for
carbapenem-resistant Enterobacteriaceae (CRE)
took an average of 387 days following hospital discharge
to be clear of the organism
http://www.cdc.gov/mmwr/preview/mmwr...cid=mm6209a3_wCRE are important for several reasons. First, invasive infections (e.g., bloodstream infections) with CRE are associated with mortality rates exceeding 40% (5); this is significantly higher than mortality rates observed for carbapenem-susceptible Enterobacteriaceae. Of note, because the majority of positive cultures were from urine, overall in-hospital mortality rates associated with positive cultures were lower in the EIP CRE surveillance (4%). Second, carbapenem-resistant strains frequently possess additional resistance mechanisms that render them resistant to most available antimicrobials; pan-resistant CRE have been reported (9). Further, novel antimicrobials for multidrug-resistant gram-negative bacilli are in early stages of development and not likely to be available soon (10). Third, CRE can spread rapidly in health-care settings (11,12). Fourth, Enterobacteriaceae are a common cause of community infections, and CRE have the potential to move from their current niche among health-care–exposed patients into the community (13). Multidrug-resistance is a problem in other gram-negative bacilli such as Pseudomonas and Acinetobacter species. However, these organisms are a less common cause of health-care infections and have less potential to spread resistance to other bacteria and into the community (2).
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