Magicman
10-22-2008, 09:00 AM
Make sure to save this to your documents
as this info can be very beneficial...Please Repost!
Video: Learn more about Glutathione:
http://www.youtube.com/watch?v=JFPUzjUDhTc
http://www.youtube.com/watch?v=Eh2PYQBICWs
Summary:
You MUST get vitamin C, B and D as the basics. This is a crucial vitamin to helping fight Avia tion Bi rd Flu. They all become enhanced with the Glutathione Cycle. Take 300 miligrams, and/or drink Orange Juice. Antioxidants, particularly glutathione and vitamin E, block the ability of the virus to enter the cells. You must eat greens like spinach or broccolli. Preferably raw uncooked spinach and broccoli has some of the highest amount of glutathione produced. I've also heard that colloidal silver can fight against it as well. Besides, any cause or alarm for this flu this can help your overall wellness and immune system as well as fatigue and mental clarity. It's also important to buy a liver detox as Glutathione produces ONLY when the liver is functional as anything toxic to the liver such as alcohol and the list below is harmful and preventing the production of the Glutathione cycle. The herb milk-thistle which you can get at any vitamin Shop or GNC store is an excellent source of the antioxidant compound silymarin which may be helpful to prevent glutathione depletion in the liver.
Here is a list of supplements to take.. This will provide a layer of strength as a preventative from the flu or many other ailments affecting the immune system; many are listed within the summary.
There are various antioxidants, anti-viral and anti-inflammatory substances you can use to help prevent or treat this from happening. Some easier and cheaper then others to purchase. However, Glutathione is the bodies main antioxidant and very important to sustain a perfect immune system.
What foods contain Glutatione?
Asparagus, avocado, spinach and walnuts are particularly rich dietary sources of glutathione and here's more.
Kail
Watercrest
Cabbage
Spinach
Garlic
Bio-active Whey Protein
Brocolli
watermelon
grapefruit
potato
acorn squash
strawberries
orange
tomato
cantaloupe
okra
peach
zucchini
Foods that contain Cysteine; an essential amino acid for Glutathione production:
ricotta
cottage cheese
yogurt
pork
sausage meat
chicken
turkey
duck
luncheon meat
wheat germ
granola
oat flakes.
What that attacks the Immune system?
----------------------------------------------------
Steroids
Alcohol
Antibiotics
Anti-depressants
Processed foods
Smoking
Caffeine
Cigarettes
Mercury
Fluoride
Chemicals
Pesticides
Certain prescriptions (Research the one your taking)
Antioxidants/Amino Acids
---------------------------
Glutathione (Take Vitamins C and B6 with it) Needs 3 amino acids to break it down. These are cysteine, glutamic acid and glycine - three of the twenty two amino acids which comprise the building blocks of all known proteins. In general, the amino-end of one amino acid combines with the acid-end of another to form a peptide bond with the elimination of water. Chains of amino acids are called proteins.
"Glutathione is a ubiquitous tripeptide molecule, consisting of three amino acids joined together. The sequence of amino acids and the arrangement in space of each peptide bond defines some specific structural features of all proteins and olegopeptides (few amino acids in sequence) that relate to their function. In order to convert the amino acids you need vitamin B6, B12, and folate.
High levels of homocysteine will be toxic ..s that line the arteries which will make the blood prone to clotting and promote bad cholesterol (LDL) which will be deposited as plaque in blood vessels. You must do the full cycle in order for them to not be overproduced!
Functions of Glutathione
---------------------------------------
Enhancing the Immune System - Your bodies immune activity, involving unimpeded multiplication of lymphocytes and antibody production, requires maintenance of normal levels of glutathione inside the lymphocytes. Antioxidant and Free Radical Scavenger - Glutathione plays a central protective role against the damaging effects of bacteria, viruses, pollutants and free radicals.
Regulator of Other Antioxidants - Without glutathione, other important antioxidants such as vitamins C and E cannot do their job adequately to protect your body against disease.
A Detoxifying Agent - Another major function of glutathione is in the detoxification of foreign chemical compounds such as carcinogens and harmful metabolites.
Recommended Glutathione Product
-------------------------------------------------------
This site is recommended to purchase powder Glutathione which is very potent. Organic, pesticide and chemical-free. There are many others but this is a genuine product and it's cheap. When in this form it is much more effective then any pill or capsule taken as it needs to cover the whole intestinal tract.
http://organicpharmacy.org/products/Renew.Pro
More Glutathione Article:
-------------------------------------
http://www.prohealth.com/library/showarticle.cfm?id=2890&t=CFIDS_FM
New Study Shows Raised Glutathione Levels Help Balance Immune System
November 7, 2000
Researchers from Germany and the US have found that N-acetylcysteine (NAC) can boost the natural antioxidant system of the body. The body carries many antioxidant defense systems, but inside cells a small protein called glutathione is crucial. Glutathione is essential for the function of immune cells, which protect us from viral and bacterial infections. In people with immune deficiency, glutathione levels fall well below the normal levels in blood and immune cells. Restoring glutathione levels to those found in healthy people is likely to help immune deficient patients. Two studies have recently been published with research backing up the claims that NAC helps fight disease, one in the European Journal of Clinical Investigation, from Stig Froland in Oslo, Norway, and the other by Leonore and Leonard Herzenberg, a husband and wife team from Stanford, California. The results of their work showed that glutathione levels could indeed be restored in AIDS patients and that this may improve the outlook for these patients. Herzenberg and colleagues conducted a clinical trial in which 31 HIV-infected patients were given daily doses of N-acetylcysteine (NAC) — a glutathione precursor — and 30 others were given a benign sugar pill. According to the study published in the October 1 issue of the European Journal of Clinical Investigation, those taking NAC had increased the amount of glutathione in their bodies to near-normal levels at the end of the two-month trial. "The importance here is that glutathione is a central component of all cells, and glutathione deficiency is associated with poor prognosis in many, many diseases," said Herzenberg. "What we've proven is that giving people NAC replenishes the glutathione stores." The authors of the report concluded that "NAC offers useful adjunct therapy to increase protection against oxidative stress, improve immune system function and increase detoxification of acetaminophen and other drugs. These findings suggest NAC therapy could be valuable in other clinical situations in which there is GSH deficiency." This finding is important because another investigator, Wulf Droge recently reported in the Journal of Molecular Medicine that administration of NAC not only increases glutathione but also improves immune cell function. In particular the function of a key component of the immune system, the T-lymphocytes, improved dramatically. "It is important to realize that these results are the culmination of over 10 years of research." states Frank Staal, an immunologist from Rotterdam, The Netherlands, who worked in this field for many years. "The groups of Droge and Herzenberg were the first to demonstrate that glutathione is low in AIDS and that this defect contributes to poor immune cell function.
http://www.prozactruth.com/gluta.htm
What is Glutathione?
Glutathione is a small molecule made up of three amino acids, which exists in almost every cell of the body. However, glutathione, must be generated within the cell from its precursors before it can work effectively in the body. The presence of glutathione is required to maintain the normal function of the immune system. It is known to play a critical role in the multiplication of lymphocytes (the cells that mediate specific immunity) which occurs in the development of an effective immune response.
Furthermore, the cells of the immune system produce many oxiradicals as a result of their normal functioning, resulting in a need for higher concentrations of antioxidants than most cells. Glutathione plays a crucial role in fulfilling this requirement.
How to Make Glutathione Naturally Within the Body
There are several ways a body can manufacture glutathione. It is true it takes 3 amino acids for the body to manufacture glutathione but our bodies can take food, turn the foods into the substance to manufacture the 3 needed amino acids needed to manufacture glutathione. This is also the natural method for a body to create glutathione. As an example, asparagus and watermelon will make glutathione.
With all of the breaking news regarding glutathione as an antioxidant as well as part of the reason for the development of autism, many supplements are suddenly jumping on the glutathione bandwagon.
Glutathione is not new to this Web Site. We have been recommending glutathione for the past 10 years to assist individuals to taper off psychotropic medications. One thing that has been overlooked by many still is the role of glutathione within the liver as well as the role of glutathione transporting a toxin to the liver. There is considerable more to glutathione than having it in the cells. The whey proteins mentioned on this site do make intracellular glutathione. However, like most other things in life, not all things are equal.
When you need intracellular glutathione quickly, the best method and safest method is with a whey protein. We have reviewed the top selling whey proteins. One whey protein stands so far above all others it is amazing.
When you look at the charts from the link above, keep in mind the Immune Pro and the Renew Pro are also from disease-free, pesticide-free, chemical-free, natural grass pasture fed cows. Hormone treatment-free and Genetically Modified-free. To top it off, the Immune Pro and Renew Pro are lower in price.
We recommend the Renew Pro over the Immune Pro. Reason: We have found the Immune Pro is actually a little too strong and the taste is bland. Compliance with the Immune Pro is no where as high as with the Renew Pro. When you want and need intracellular glutathione, nothing compares.
You can purchase the Renew Pro from TRB Health at the best price. TRB Health manufactures nutritional products used primarily for drug detoxification and drug withdrawal by medical doctors and psychiatrist. RenewPro is one product used when a patient has anxiety, fatigue or depression. If you are not taking medication the results are even more staggering. If by chance you are taking any addictive medication or drug you should feel the positive difference rather quickly as well.
Increasing intracellular levels of glutathione is critical with drug withdrawal and it is vitally important that any supplement not cause a drug/supplement interaction. This is also why we recommend RenewPro.
Additional Glutathione Information
The non-essential amino acid homocysteine is produced in the body with the metabolism of the amino acid methionine.
Homocysteine is usually broken down into the amino acid cysteine. Cysteine is one of the amino acids needed by the cells to make intracellular glutathione. If your body does not convert homocysteine to cysteine the intracellular glutathione conversion will not take place.
The rapid conversion of homocysteine is critical. If conversion takes place too slow, homocysteine will accumulate in the body and damage cell membranes, damage blood vessels, increase the risk of cardiovascular disease, and atherosclerosis.
Rapid conversion of homocysteine requires an individual to have adequate amount of vitamin B6, B12, and folate. Over 50% of the population in the world has a genetic defect in the pathway needed to metabolize B6, B12, and folate. The site mentioned above, www. trbhealth. com also has a sublingual vitamin B6, B12 and folate.
Metabolism of homocysteine (sulphur-containing amino acid) is accomplished in the remethylation cycle where vitamin B12 and folic acid are essential coenzymes and degraded to methionine or through transsulfuration, which use as cofactors folate, vitamin B6 and vitamin B12 and is degraded to cystathionine.
The physician can check for hyperhomocysteine (higher than normal amount of homocysteine) with a blood test. Many medication side effects, physiological symptomology and other body and mental symptoms can be eliminated with treatment with vitamins B6, B12 and folate.
Age is a factor of B6, B12 and folate metabolism despite an individuals DNA. With age, the enzyme needed to metabolize B6, B12 and folate will be depleted and the need to supplement through nutrition increases proportionally.
High levels of homocysteine will be toxic ..s that line the arteries which will make the blood prone to clotting and promote bad cholesterol (LDL) which will be deposited as plaque in blood vessels.
Cysteine helps to detoxify toxins and protect the body from radiation damage. Cysteine as well as selenium work hand in hand with vitamin E. Cysteine also needs selenium to be effective.
Cysteine will bind with soluble iron, chelates heavy metals, and breaks down mucus in the respiratory tract, beneficial for bronchitis, emphysema, and tuberculosis.
Of note: Cysteine as a stand-alone supplement should be avoided due to toxicity.
Cysteine is the pre-cursor to glutathione, the body's natural antioxidant. Glutathione regulates the antioxidant redox state, and allows the body to recycle its store of antioxidants including: vitamin A, C, E and Co-enzyme Q10.
Free cysteine is unstable and is readily oxidized producing compounds that could have harmful effects. Glutathione cannot be absorbed by cells and so must be re-synthesized intracellularly.
Glutathione is the antioxidant that is prevalent in every cell in the human body. Glutathione is primarily synthesized in the liver where it is abundantly present.
80-90% of the blood that leaves the stomach and intestines passes through the liver. The blood carries important nutrients to the liver where they are metabolized into substances vital to life. In the same way, exogenous toxic substances reach the liver where they are either activated or transformed into less toxic derivatives. Glutathione plays a crucial role in the liver's biotransformation system.
The liver biotransformation system comprises important functions:
1. Filtering alcohol and other toxic substances from the blood.
2. Processing drugs and medications absorbed through the digestive system, enabling the body to use them effectively and ultimately dispose of them.
The liver uses glutathione to process; alcohol, caffeine, medications, nicotine as an example, to process such substances and remove them from the blood. Cysteine is the limiting factor in glutathione synthesis, ensuring an adequate supply of glutathione helps cleanse the blood of toxins and substances.
The role of glutathione and its inter-workings with alcohol and the metabolism has received the attention of scientist for years. With alcohol metabolism using the P 450 enzymes, much of the alcohol studies can be transformed into applicable knowledge with antidepressants and other medications that use the same system.
Ethanol and Glutathione
Reduced glutathione plays a critical role in the cellular detoxification processes including the metabolism of peroxides, the conjugation with electrophils and the scavenging of the free radicals. The relevance of glutathione in ethanol metabolism consists mainly in compensating for alcohol-related oxidative stress. Oxidative stress is a disturbance in the pro-oxidant/antioxidant balance (increased pro-oxidant levels), which may be achieved by either an enhancement of oxidative reactions leading to the increased formation of reactive oxygen species (ROS) or by a decrease of the antioxidant defense.
Whether you are working with alcohol or most medications, both will activate the microsomal Cytochrome P450-dependant enzyme system, especially the subclass CYP2E1, that plays an important role in the liver detoxification. With antidepressants it will usually be with the subclass CYP2D6 or the CYP2C9 pathways.
Glutathione (GSH) will be depleted within the cells and liver and also in other organs in the body due to the absorption of toxins by glutathione.
The Creation of Glutathione
Knowing the theory of glutathione is useful but without the correct application of the data it is pointless.
Increasing glutathione intracellularly can be done in only a few ways. Using a whey protein designed in such a way to present to the cells the required amino acids in the exact sequence or by nutrients and or foods.
The natural way for our body to produce intracellular glutathione is with all natural nutrients. This is also how I recommend an individual increase intracellular glutathione if possible. However, with knowing 50% of the population has the genetic makeup that gets in the way of the body's ability to create glutathione naturally from food, a whey protein may be your best answer.
Why?
Imagine you have a car that will not start because the battery is low in power. You can give the car a jumpstart and drive down the road but the chances are you will need to keep getting a jumpstart every time you wish to drive.
The above example is what is happening when you bypass the natural structure of the body.
If you were to fill the battery with water and put it on a slow charge until it was at full power you should not have to rely on a jumpstart again.
This example is what should take place within the body regarding the creation of glutathione.
Putting the correct nutrients in the body and allowing the body to use the nutrients to eventually manufacture glutathione not only gets those body parts working again but also promotes long-term health.
Your body can manufacture glutathione with the correct nutrients.
If you have been told it takes one of these whey proteins to manufacture glutathione and that is the only way to do it, someone has lied to you.
Glutathione as a Detoxicant
Supplemental detoxicants become necessary as our environment becomes increasingly polluted. Our food and water sources are contaminated with chemicals. One of our main defenses against pollutants is glutathione, which is present in the liver in high concentrations. Glutathione acts as a detoxifying agent by combining with undesirable substances and ridding the body of them through urine and bile. It is important to note that unless the Colon, Liver and Blood are also detoxified, the benefits of Glutathione as a detoxicant may be minimized.
To Get a Little More Technical About Glutathione
"Glutathione is a ubiquitous tripeptide molecule, consisting of three amino acids joined together. These are cysteine, glutamic acid and glycine - three of the twenty two amino acids which comprise the building blocks of all known proteins. In general, the amino-end of one amino acid combines with the acid-end of another to form a peptide bond with the elimination of water. Chains of amino acids are called proteins. The sequence of amino acids and the arrangement in space of each peptide bond defines some specific structural features of all proteins and olegopeptides (few amino acids in sequence) that relate to their function.
Glutathione (Psychoneurobiology)
"Free radicals and oxyradicals have been recognized by psychoneurobiologist as playing an important role in the development and progression of many of these disorders. The brain is particularly susceptible to free radical attack because it generates more oxidative-by-products per gram of tissue than any other organ. The brain's main antioxidant is glutathione- it's importance cannot be overstated.
Oxidative stress and glutathione are important factors in such various disorders as brain injury, neurodegenerative disease, schizophrenia, Down syndrome and other pathologies.
Disorders of the brain and nervous system that are linked to oxidative stress
Brain Injury Neurodegenerative
disease Others
Brain injury Parkinson's disease Schizophrenia
Trauma Alzheimer's dementia Down syndrome
Stroke Multiple sclerosis (MS) Tardive dyskinesia
Ischemia Lou Gehrig's disease (ALS) Sleep deprivation
Toxicity of lead, mercury, etc.
Lipofuscinosis (Batten's disease) Huntington's chorea
"Many neurological and psychiatric disease processes are characterized by high levels of oxidative stress and free radical formation, as well as abnormalities in glutathione metabolism and antioxidant defenses.
Source Dr. Gutman M.D.
Glutathione GSH
Dr. Perlmutter: "Eighty to ninety percent improve dramatically. It's felt that the mechanism that allows it to work is in increasing the sensitivity to certain receptors to dopamine. Glutathione doesn't raise dopamine levels, but it allows the dopamine in the brain to be more effective. That's not a new idea in medicine. Diabetic drugs work not by increasing insulin, but by increasing the receptors to insulin. Glutathione not only increases sensitivity to dopamine, but also to serotonin, which may explain why many of our depressed PD patients have a remarkable improvement.
Increasing glutathione in the body has been proven to be essential in the treatment of disease. Antidepressants and other medications deplete the body and brain of glutathione.
-------------------------------------------------------------
Boost your immune system
Glutathione is important in maintaining your overall good health and wellbeing since it neutralizes harmful free radicals, flushes away toxins, supports cell health and integrity, and strengthens immune system activity. L-Glutathione, a tripeptide made up of three amino acids called cysteine, glycine, and glutamic acid, is produced by the body. It is found in high concentrations in the liver, where it binds to heavy metals such as mercury and lead, as well as chemical pollutants, and transforms them into a form that can be easily flushed out of the body via enzymatic pathways.
Reduced L-Glutathione has been formulated to improve absorbability and activity and is the only active form that can react to foreign toxins and remove them from the body. Taken as directed, it can strengthen your immune system and make you less susceptible to catching the Bird Flu virus and may allow your body to fight off the virus.
-------------------------------------------------------------
How to enhance Glutathione intake:
1.N-Acetyl-Cysteine (NAC)
It is derived from the amino acid L-Cysteine, and acts as a precursor of glutathione. NAC is quickly metabolized into glutathione once it enters the body. It has been proven in numerous scientific studies and clinical trials, to boost intracellular production of glutathione, and is approved by the FDA for treatment of accetaminophen overdose. Because of glutathione's mucolytic action, NAC (brand name Mucomyst) is commonly used in the treatment of lung diseases like cystic fibrosis, bronchitis and asthma.
2.Milk Thistle, Silymarin
Milk thistle is a powerful antioxidant and supports the liver by preventing the depletion of glutathione. Silymarin is the active compound of milk thistle. It is a natural liver detoxifier and protects the liver from many industrial toxins such as carbon tetrachloride, and more common agents like alcohol.
3.Alpha Lipoic Acid
Made naturally in body cells as a by-product of energy release, ALA increases the levels of intra-cellular glutathione, and is a natural antioxidant with free radical scavenging abilities. It has the ability to regenerate oxidized antioxidants like Vitamin C and E and helps to make them more potent. ALA is also known for its ability to enhance glucose uptake and may help prevent the cellular damage accompanying the complications of diabetes. It also has a protective effect in the brain.
4.Natural Foods That Boost Glutathione Levels
Asparagus is a leading source of glutathione. Foods like broccoli (2), avocado and spinach are also known to boost glutathione levels. Raw eggs, garlic and fresh unprocessed meats contain high levels of sulphur-containing amino acids and help to maintain optimal glutathione levels.
5.Undenatured Whey Protein Isolate
Whey protein contains proteins like alpha-lactalbumin which is is rich in sulphur-containing amino acids. Heating or pasteurization destroys the delicate disulphide bonds that give these proteins their bioactivity. Undenatured whey protein is a non-heated product that preserves bioactive amino acids like cystine. It has been shown in numerous scientific studies and clinical trials to optimize glutathione levels.
6.Curcumin (Turmeric)
Treatment of brain cells called astrocytes, with the Indian curry spice, curcumin (turmeric) has been found to increase expression of the glutathione S-transferase and protect neurons exposed to oxidant stress.
7.Balloon Flower Root
Changkil saponins (CKS) isolated from the roots of the Chinese herbal medicine, Platycodon grandiflorum A. DC (Campanulaceae), commonly called Balloon Flower Root or Jie Geng, have been found to increase intracellular glutathione (GSH) content and significantly reduce oxidative injury to liver cells, minimise cell death and lipid peroxidation.
8.Selenium
Selenium is a co-factor for the enzyme glutathione peroxidase. Selenium supplements have become popular because some studies suggest they may play a role in decreasing the risk of certain cancers, and in how the immune system and the thyroid gland function. However, too much selenium can cause some toxic effects including gastrointestinal upset, brittle nails, hair loss and mild nerve damage.
Disclaimer: The information here is not provided by medical professionals and is not intended as a substitute for medical advice. Nutritional supplements, while usually benign, can produce adverse reactions in some people. As with prescribed drugs, long-term effects from supplements are often unknown. Pregnant women and children should not take supplements except after consultation with their healthcare provider. Never exceed the recommended dosage on the container. If you observe adverse effects stop taking the supplement immediately and contact your healthcare provider.
References:
1. The systemic availability of oral glutathione Witschi A, Reddy S, Stofer B, Lauterburg BH. [Eur J Clin Pharmacol. 1992;43(6):667-9.
2. Dietary approach to attenuate oxidative stress, hypertension, and inflammation in the cardiovascular system Wu L, Ashraf MH, Facci M, Wang R, Paterson PG, Ferrie A, Juurlink BH. [Proc Natl Acad Sci U S A. 2004 May 4;101(18):7094-9. Epub 2004 Apr 21
3.
Can Curry Protect Against Alzheimer’s? American Physiological Society (APS) Press release; 16-Apr-2004
4. Protective effect of saponins derived from roots of Platycodon grandiflorum on tert-butyl hydroperoxide-induced oxidative hepatotoxicity Lee KJ, Choi CY, Chung YC, Kim YS, Ryu SY, Roh SH, Jeong HG. [Toxicol Lett. 2004 Mar 7;147(3):271-82.
Copyright © 2004 Priya Shah
-----------------------------------------------------------------------------------------------------
Silver colloidal which can help fight the bi rd flu:
http://vitanetonline.com/description/SN0354/vitamins/ColloidaLife-Trace-Minerals
http://vitanetonline.com/description/FB0122/vitamins/Silver-(Colloidal)
as this info can be very beneficial...Please Repost!
Video: Learn more about Glutathione:
http://www.youtube.com/watch?v=JFPUzjUDhTc
http://www.youtube.com/watch?v=Eh2PYQBICWs
Summary:
You MUST get vitamin C, B and D as the basics. This is a crucial vitamin to helping fight Avia tion Bi rd Flu. They all become enhanced with the Glutathione Cycle. Take 300 miligrams, and/or drink Orange Juice. Antioxidants, particularly glutathione and vitamin E, block the ability of the virus to enter the cells. You must eat greens like spinach or broccolli. Preferably raw uncooked spinach and broccoli has some of the highest amount of glutathione produced. I've also heard that colloidal silver can fight against it as well. Besides, any cause or alarm for this flu this can help your overall wellness and immune system as well as fatigue and mental clarity. It's also important to buy a liver detox as Glutathione produces ONLY when the liver is functional as anything toxic to the liver such as alcohol and the list below is harmful and preventing the production of the Glutathione cycle. The herb milk-thistle which you can get at any vitamin Shop or GNC store is an excellent source of the antioxidant compound silymarin which may be helpful to prevent glutathione depletion in the liver.
Here is a list of supplements to take.. This will provide a layer of strength as a preventative from the flu or many other ailments affecting the immune system; many are listed within the summary.
There are various antioxidants, anti-viral and anti-inflammatory substances you can use to help prevent or treat this from happening. Some easier and cheaper then others to purchase. However, Glutathione is the bodies main antioxidant and very important to sustain a perfect immune system.
What foods contain Glutatione?
Asparagus, avocado, spinach and walnuts are particularly rich dietary sources of glutathione and here's more.
Kail
Watercrest
Cabbage
Spinach
Garlic
Bio-active Whey Protein
Brocolli
watermelon
grapefruit
potato
acorn squash
strawberries
orange
tomato
cantaloupe
okra
peach
zucchini
Foods that contain Cysteine; an essential amino acid for Glutathione production:
ricotta
cottage cheese
yogurt
pork
sausage meat
chicken
turkey
duck
luncheon meat
wheat germ
granola
oat flakes.
What that attacks the Immune system?
----------------------------------------------------
Steroids
Alcohol
Antibiotics
Anti-depressants
Processed foods
Smoking
Caffeine
Cigarettes
Mercury
Fluoride
Chemicals
Pesticides
Certain prescriptions (Research the one your taking)
Antioxidants/Amino Acids
---------------------------
Glutathione (Take Vitamins C and B6 with it) Needs 3 amino acids to break it down. These are cysteine, glutamic acid and glycine - three of the twenty two amino acids which comprise the building blocks of all known proteins. In general, the amino-end of one amino acid combines with the acid-end of another to form a peptide bond with the elimination of water. Chains of amino acids are called proteins.
"Glutathione is a ubiquitous tripeptide molecule, consisting of three amino acids joined together. The sequence of amino acids and the arrangement in space of each peptide bond defines some specific structural features of all proteins and olegopeptides (few amino acids in sequence) that relate to their function. In order to convert the amino acids you need vitamin B6, B12, and folate.
High levels of homocysteine will be toxic ..s that line the arteries which will make the blood prone to clotting and promote bad cholesterol (LDL) which will be deposited as plaque in blood vessels. You must do the full cycle in order for them to not be overproduced!
Functions of Glutathione
---------------------------------------
Enhancing the Immune System - Your bodies immune activity, involving unimpeded multiplication of lymphocytes and antibody production, requires maintenance of normal levels of glutathione inside the lymphocytes. Antioxidant and Free Radical Scavenger - Glutathione plays a central protective role against the damaging effects of bacteria, viruses, pollutants and free radicals.
Regulator of Other Antioxidants - Without glutathione, other important antioxidants such as vitamins C and E cannot do their job adequately to protect your body against disease.
A Detoxifying Agent - Another major function of glutathione is in the detoxification of foreign chemical compounds such as carcinogens and harmful metabolites.
Recommended Glutathione Product
-------------------------------------------------------
This site is recommended to purchase powder Glutathione which is very potent. Organic, pesticide and chemical-free. There are many others but this is a genuine product and it's cheap. When in this form it is much more effective then any pill or capsule taken as it needs to cover the whole intestinal tract.
http://organicpharmacy.org/products/Renew.Pro
More Glutathione Article:
-------------------------------------
http://www.prohealth.com/library/showarticle.cfm?id=2890&t=CFIDS_FM
New Study Shows Raised Glutathione Levels Help Balance Immune System
November 7, 2000
Researchers from Germany and the US have found that N-acetylcysteine (NAC) can boost the natural antioxidant system of the body. The body carries many antioxidant defense systems, but inside cells a small protein called glutathione is crucial. Glutathione is essential for the function of immune cells, which protect us from viral and bacterial infections. In people with immune deficiency, glutathione levels fall well below the normal levels in blood and immune cells. Restoring glutathione levels to those found in healthy people is likely to help immune deficient patients. Two studies have recently been published with research backing up the claims that NAC helps fight disease, one in the European Journal of Clinical Investigation, from Stig Froland in Oslo, Norway, and the other by Leonore and Leonard Herzenberg, a husband and wife team from Stanford, California. The results of their work showed that glutathione levels could indeed be restored in AIDS patients and that this may improve the outlook for these patients. Herzenberg and colleagues conducted a clinical trial in which 31 HIV-infected patients were given daily doses of N-acetylcysteine (NAC) — a glutathione precursor — and 30 others were given a benign sugar pill. According to the study published in the October 1 issue of the European Journal of Clinical Investigation, those taking NAC had increased the amount of glutathione in their bodies to near-normal levels at the end of the two-month trial. "The importance here is that glutathione is a central component of all cells, and glutathione deficiency is associated with poor prognosis in many, many diseases," said Herzenberg. "What we've proven is that giving people NAC replenishes the glutathione stores." The authors of the report concluded that "NAC offers useful adjunct therapy to increase protection against oxidative stress, improve immune system function and increase detoxification of acetaminophen and other drugs. These findings suggest NAC therapy could be valuable in other clinical situations in which there is GSH deficiency." This finding is important because another investigator, Wulf Droge recently reported in the Journal of Molecular Medicine that administration of NAC not only increases glutathione but also improves immune cell function. In particular the function of a key component of the immune system, the T-lymphocytes, improved dramatically. "It is important to realize that these results are the culmination of over 10 years of research." states Frank Staal, an immunologist from Rotterdam, The Netherlands, who worked in this field for many years. "The groups of Droge and Herzenberg were the first to demonstrate that glutathione is low in AIDS and that this defect contributes to poor immune cell function.
http://www.prozactruth.com/gluta.htm
What is Glutathione?
Glutathione is a small molecule made up of three amino acids, which exists in almost every cell of the body. However, glutathione, must be generated within the cell from its precursors before it can work effectively in the body. The presence of glutathione is required to maintain the normal function of the immune system. It is known to play a critical role in the multiplication of lymphocytes (the cells that mediate specific immunity) which occurs in the development of an effective immune response.
Furthermore, the cells of the immune system produce many oxiradicals as a result of their normal functioning, resulting in a need for higher concentrations of antioxidants than most cells. Glutathione plays a crucial role in fulfilling this requirement.
How to Make Glutathione Naturally Within the Body
There are several ways a body can manufacture glutathione. It is true it takes 3 amino acids for the body to manufacture glutathione but our bodies can take food, turn the foods into the substance to manufacture the 3 needed amino acids needed to manufacture glutathione. This is also the natural method for a body to create glutathione. As an example, asparagus and watermelon will make glutathione.
With all of the breaking news regarding glutathione as an antioxidant as well as part of the reason for the development of autism, many supplements are suddenly jumping on the glutathione bandwagon.
Glutathione is not new to this Web Site. We have been recommending glutathione for the past 10 years to assist individuals to taper off psychotropic medications. One thing that has been overlooked by many still is the role of glutathione within the liver as well as the role of glutathione transporting a toxin to the liver. There is considerable more to glutathione than having it in the cells. The whey proteins mentioned on this site do make intracellular glutathione. However, like most other things in life, not all things are equal.
When you need intracellular glutathione quickly, the best method and safest method is with a whey protein. We have reviewed the top selling whey proteins. One whey protein stands so far above all others it is amazing.
When you look at the charts from the link above, keep in mind the Immune Pro and the Renew Pro are also from disease-free, pesticide-free, chemical-free, natural grass pasture fed cows. Hormone treatment-free and Genetically Modified-free. To top it off, the Immune Pro and Renew Pro are lower in price.
We recommend the Renew Pro over the Immune Pro. Reason: We have found the Immune Pro is actually a little too strong and the taste is bland. Compliance with the Immune Pro is no where as high as with the Renew Pro. When you want and need intracellular glutathione, nothing compares.
You can purchase the Renew Pro from TRB Health at the best price. TRB Health manufactures nutritional products used primarily for drug detoxification and drug withdrawal by medical doctors and psychiatrist. RenewPro is one product used when a patient has anxiety, fatigue or depression. If you are not taking medication the results are even more staggering. If by chance you are taking any addictive medication or drug you should feel the positive difference rather quickly as well.
Increasing intracellular levels of glutathione is critical with drug withdrawal and it is vitally important that any supplement not cause a drug/supplement interaction. This is also why we recommend RenewPro.
Additional Glutathione Information
The non-essential amino acid homocysteine is produced in the body with the metabolism of the amino acid methionine.
Homocysteine is usually broken down into the amino acid cysteine. Cysteine is one of the amino acids needed by the cells to make intracellular glutathione. If your body does not convert homocysteine to cysteine the intracellular glutathione conversion will not take place.
The rapid conversion of homocysteine is critical. If conversion takes place too slow, homocysteine will accumulate in the body and damage cell membranes, damage blood vessels, increase the risk of cardiovascular disease, and atherosclerosis.
Rapid conversion of homocysteine requires an individual to have adequate amount of vitamin B6, B12, and folate. Over 50% of the population in the world has a genetic defect in the pathway needed to metabolize B6, B12, and folate. The site mentioned above, www. trbhealth. com also has a sublingual vitamin B6, B12 and folate.
Metabolism of homocysteine (sulphur-containing amino acid) is accomplished in the remethylation cycle where vitamin B12 and folic acid are essential coenzymes and degraded to methionine or through transsulfuration, which use as cofactors folate, vitamin B6 and vitamin B12 and is degraded to cystathionine.
The physician can check for hyperhomocysteine (higher than normal amount of homocysteine) with a blood test. Many medication side effects, physiological symptomology and other body and mental symptoms can be eliminated with treatment with vitamins B6, B12 and folate.
Age is a factor of B6, B12 and folate metabolism despite an individuals DNA. With age, the enzyme needed to metabolize B6, B12 and folate will be depleted and the need to supplement through nutrition increases proportionally.
High levels of homocysteine will be toxic ..s that line the arteries which will make the blood prone to clotting and promote bad cholesterol (LDL) which will be deposited as plaque in blood vessels.
Cysteine helps to detoxify toxins and protect the body from radiation damage. Cysteine as well as selenium work hand in hand with vitamin E. Cysteine also needs selenium to be effective.
Cysteine will bind with soluble iron, chelates heavy metals, and breaks down mucus in the respiratory tract, beneficial for bronchitis, emphysema, and tuberculosis.
Of note: Cysteine as a stand-alone supplement should be avoided due to toxicity.
Cysteine is the pre-cursor to glutathione, the body's natural antioxidant. Glutathione regulates the antioxidant redox state, and allows the body to recycle its store of antioxidants including: vitamin A, C, E and Co-enzyme Q10.
Free cysteine is unstable and is readily oxidized producing compounds that could have harmful effects. Glutathione cannot be absorbed by cells and so must be re-synthesized intracellularly.
Glutathione is the antioxidant that is prevalent in every cell in the human body. Glutathione is primarily synthesized in the liver where it is abundantly present.
80-90% of the blood that leaves the stomach and intestines passes through the liver. The blood carries important nutrients to the liver where they are metabolized into substances vital to life. In the same way, exogenous toxic substances reach the liver where they are either activated or transformed into less toxic derivatives. Glutathione plays a crucial role in the liver's biotransformation system.
The liver biotransformation system comprises important functions:
1. Filtering alcohol and other toxic substances from the blood.
2. Processing drugs and medications absorbed through the digestive system, enabling the body to use them effectively and ultimately dispose of them.
The liver uses glutathione to process; alcohol, caffeine, medications, nicotine as an example, to process such substances and remove them from the blood. Cysteine is the limiting factor in glutathione synthesis, ensuring an adequate supply of glutathione helps cleanse the blood of toxins and substances.
The role of glutathione and its inter-workings with alcohol and the metabolism has received the attention of scientist for years. With alcohol metabolism using the P 450 enzymes, much of the alcohol studies can be transformed into applicable knowledge with antidepressants and other medications that use the same system.
Ethanol and Glutathione
Reduced glutathione plays a critical role in the cellular detoxification processes including the metabolism of peroxides, the conjugation with electrophils and the scavenging of the free radicals. The relevance of glutathione in ethanol metabolism consists mainly in compensating for alcohol-related oxidative stress. Oxidative stress is a disturbance in the pro-oxidant/antioxidant balance (increased pro-oxidant levels), which may be achieved by either an enhancement of oxidative reactions leading to the increased formation of reactive oxygen species (ROS) or by a decrease of the antioxidant defense.
Whether you are working with alcohol or most medications, both will activate the microsomal Cytochrome P450-dependant enzyme system, especially the subclass CYP2E1, that plays an important role in the liver detoxification. With antidepressants it will usually be with the subclass CYP2D6 or the CYP2C9 pathways.
Glutathione (GSH) will be depleted within the cells and liver and also in other organs in the body due to the absorption of toxins by glutathione.
The Creation of Glutathione
Knowing the theory of glutathione is useful but without the correct application of the data it is pointless.
Increasing glutathione intracellularly can be done in only a few ways. Using a whey protein designed in such a way to present to the cells the required amino acids in the exact sequence or by nutrients and or foods.
The natural way for our body to produce intracellular glutathione is with all natural nutrients. This is also how I recommend an individual increase intracellular glutathione if possible. However, with knowing 50% of the population has the genetic makeup that gets in the way of the body's ability to create glutathione naturally from food, a whey protein may be your best answer.
Why?
Imagine you have a car that will not start because the battery is low in power. You can give the car a jumpstart and drive down the road but the chances are you will need to keep getting a jumpstart every time you wish to drive.
The above example is what is happening when you bypass the natural structure of the body.
If you were to fill the battery with water and put it on a slow charge until it was at full power you should not have to rely on a jumpstart again.
This example is what should take place within the body regarding the creation of glutathione.
Putting the correct nutrients in the body and allowing the body to use the nutrients to eventually manufacture glutathione not only gets those body parts working again but also promotes long-term health.
Your body can manufacture glutathione with the correct nutrients.
If you have been told it takes one of these whey proteins to manufacture glutathione and that is the only way to do it, someone has lied to you.
Glutathione as a Detoxicant
Supplemental detoxicants become necessary as our environment becomes increasingly polluted. Our food and water sources are contaminated with chemicals. One of our main defenses against pollutants is glutathione, which is present in the liver in high concentrations. Glutathione acts as a detoxifying agent by combining with undesirable substances and ridding the body of them through urine and bile. It is important to note that unless the Colon, Liver and Blood are also detoxified, the benefits of Glutathione as a detoxicant may be minimized.
To Get a Little More Technical About Glutathione
"Glutathione is a ubiquitous tripeptide molecule, consisting of three amino acids joined together. These are cysteine, glutamic acid and glycine - three of the twenty two amino acids which comprise the building blocks of all known proteins. In general, the amino-end of one amino acid combines with the acid-end of another to form a peptide bond with the elimination of water. Chains of amino acids are called proteins. The sequence of amino acids and the arrangement in space of each peptide bond defines some specific structural features of all proteins and olegopeptides (few amino acids in sequence) that relate to their function.
Glutathione (Psychoneurobiology)
"Free radicals and oxyradicals have been recognized by psychoneurobiologist as playing an important role in the development and progression of many of these disorders. The brain is particularly susceptible to free radical attack because it generates more oxidative-by-products per gram of tissue than any other organ. The brain's main antioxidant is glutathione- it's importance cannot be overstated.
Oxidative stress and glutathione are important factors in such various disorders as brain injury, neurodegenerative disease, schizophrenia, Down syndrome and other pathologies.
Disorders of the brain and nervous system that are linked to oxidative stress
Brain Injury Neurodegenerative
disease Others
Brain injury Parkinson's disease Schizophrenia
Trauma Alzheimer's dementia Down syndrome
Stroke Multiple sclerosis (MS) Tardive dyskinesia
Ischemia Lou Gehrig's disease (ALS) Sleep deprivation
Toxicity of lead, mercury, etc.
Lipofuscinosis (Batten's disease) Huntington's chorea
"Many neurological and psychiatric disease processes are characterized by high levels of oxidative stress and free radical formation, as well as abnormalities in glutathione metabolism and antioxidant defenses.
Source Dr. Gutman M.D.
Glutathione GSH
Dr. Perlmutter: "Eighty to ninety percent improve dramatically. It's felt that the mechanism that allows it to work is in increasing the sensitivity to certain receptors to dopamine. Glutathione doesn't raise dopamine levels, but it allows the dopamine in the brain to be more effective. That's not a new idea in medicine. Diabetic drugs work not by increasing insulin, but by increasing the receptors to insulin. Glutathione not only increases sensitivity to dopamine, but also to serotonin, which may explain why many of our depressed PD patients have a remarkable improvement.
Increasing glutathione in the body has been proven to be essential in the treatment of disease. Antidepressants and other medications deplete the body and brain of glutathione.
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Boost your immune system
Glutathione is important in maintaining your overall good health and wellbeing since it neutralizes harmful free radicals, flushes away toxins, supports cell health and integrity, and strengthens immune system activity. L-Glutathione, a tripeptide made up of three amino acids called cysteine, glycine, and glutamic acid, is produced by the body. It is found in high concentrations in the liver, where it binds to heavy metals such as mercury and lead, as well as chemical pollutants, and transforms them into a form that can be easily flushed out of the body via enzymatic pathways.
Reduced L-Glutathione has been formulated to improve absorbability and activity and is the only active form that can react to foreign toxins and remove them from the body. Taken as directed, it can strengthen your immune system and make you less susceptible to catching the Bird Flu virus and may allow your body to fight off the virus.
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How to enhance Glutathione intake:
1.N-Acetyl-Cysteine (NAC)
It is derived from the amino acid L-Cysteine, and acts as a precursor of glutathione. NAC is quickly metabolized into glutathione once it enters the body. It has been proven in numerous scientific studies and clinical trials, to boost intracellular production of glutathione, and is approved by the FDA for treatment of accetaminophen overdose. Because of glutathione's mucolytic action, NAC (brand name Mucomyst) is commonly used in the treatment of lung diseases like cystic fibrosis, bronchitis and asthma.
2.Milk Thistle, Silymarin
Milk thistle is a powerful antioxidant and supports the liver by preventing the depletion of glutathione. Silymarin is the active compound of milk thistle. It is a natural liver detoxifier and protects the liver from many industrial toxins such as carbon tetrachloride, and more common agents like alcohol.
3.Alpha Lipoic Acid
Made naturally in body cells as a by-product of energy release, ALA increases the levels of intra-cellular glutathione, and is a natural antioxidant with free radical scavenging abilities. It has the ability to regenerate oxidized antioxidants like Vitamin C and E and helps to make them more potent. ALA is also known for its ability to enhance glucose uptake and may help prevent the cellular damage accompanying the complications of diabetes. It also has a protective effect in the brain.
4.Natural Foods That Boost Glutathione Levels
Asparagus is a leading source of glutathione. Foods like broccoli (2), avocado and spinach are also known to boost glutathione levels. Raw eggs, garlic and fresh unprocessed meats contain high levels of sulphur-containing amino acids and help to maintain optimal glutathione levels.
5.Undenatured Whey Protein Isolate
Whey protein contains proteins like alpha-lactalbumin which is is rich in sulphur-containing amino acids. Heating or pasteurization destroys the delicate disulphide bonds that give these proteins their bioactivity. Undenatured whey protein is a non-heated product that preserves bioactive amino acids like cystine. It has been shown in numerous scientific studies and clinical trials to optimize glutathione levels.
6.Curcumin (Turmeric)
Treatment of brain cells called astrocytes, with the Indian curry spice, curcumin (turmeric) has been found to increase expression of the glutathione S-transferase and protect neurons exposed to oxidant stress.
7.Balloon Flower Root
Changkil saponins (CKS) isolated from the roots of the Chinese herbal medicine, Platycodon grandiflorum A. DC (Campanulaceae), commonly called Balloon Flower Root or Jie Geng, have been found to increase intracellular glutathione (GSH) content and significantly reduce oxidative injury to liver cells, minimise cell death and lipid peroxidation.
8.Selenium
Selenium is a co-factor for the enzyme glutathione peroxidase. Selenium supplements have become popular because some studies suggest they may play a role in decreasing the risk of certain cancers, and in how the immune system and the thyroid gland function. However, too much selenium can cause some toxic effects including gastrointestinal upset, brittle nails, hair loss and mild nerve damage.
Disclaimer: The information here is not provided by medical professionals and is not intended as a substitute for medical advice. Nutritional supplements, while usually benign, can produce adverse reactions in some people. As with prescribed drugs, long-term effects from supplements are often unknown. Pregnant women and children should not take supplements except after consultation with their healthcare provider. Never exceed the recommended dosage on the container. If you observe adverse effects stop taking the supplement immediately and contact your healthcare provider.
References:
1. The systemic availability of oral glutathione Witschi A, Reddy S, Stofer B, Lauterburg BH. [Eur J Clin Pharmacol. 1992;43(6):667-9.
2. Dietary approach to attenuate oxidative stress, hypertension, and inflammation in the cardiovascular system Wu L, Ashraf MH, Facci M, Wang R, Paterson PG, Ferrie A, Juurlink BH. [Proc Natl Acad Sci U S A. 2004 May 4;101(18):7094-9. Epub 2004 Apr 21
3.
Can Curry Protect Against Alzheimer’s? American Physiological Society (APS) Press release; 16-Apr-2004
4. Protective effect of saponins derived from roots of Platycodon grandiflorum on tert-butyl hydroperoxide-induced oxidative hepatotoxicity Lee KJ, Choi CY, Chung YC, Kim YS, Ryu SY, Roh SH, Jeong HG. [Toxicol Lett. 2004 Mar 7;147(3):271-82.
Copyright © 2004 Priya Shah
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